The Medical Letter on Drugs and Therapeutics
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1487
Drugs for Rosacea
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This common, chronic inflammatory facial eruption of unknown cause is more prevalent in women than in men. Rosacea is characterized by erythema and telangiectasia, and sometimes by recurrent, progressive crops of acneiform papules and pustules, usually on the central part of the face. Some patients develop granulomas and tissue hypertrophy, which may lead to rhinophyma (a bulbous nose), particularly in men. Blepharitis and conjunctivitis are common. Keratitis and corneal scarring occur rarely.

TOPICAL THERAPY — After starting treatment with topical drugs, it may take 4-6 weeks for improvement to become visible. Metronidazole (Metrogel, and others) and azelaic acid (Finacea for rosacea; Azelex for acne) are the standard topical antimicrobials used to treat the papules and pustules of rosacea; they appear to be about equally effective, but few ... more       Show References Hide References

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Title: Drugs for Rosacea
Article code: 1487b
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