The Medical Letter on Drugs and Therapeutics
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1515
Crisaborole (Eucrisa) for Atopic Dermatitis
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The FDA has approved crisaborole 2% ointment (Eucrisa – Pfizer) for topical treatment of mild to moderate atopic dermatitis in patients ≥2 years old. It is the first phosphodiesterase type-4 (PDE4) inhibitor to be approved in the US for this indication.

ATOPIC DERMATITIS — Atopic dermatitis (also known as atopic eczema) is a chronic pruritic inflammatory skin disease that commonly presents in infancy or early childhood and is frequently associated with other atopic disorders such as allergic rhinitis and asthma. It has a relapsing course, often improving by adolescence. In infants, atopic dermatitis typically involves the face, scalp, and extensor surfaces of the limbs. In older patients, it characteristically involves the flexural areas.

STANDARD TREATMENT — Application of moisturizers, emollients, and barrier creams can reduce the need for pharmacologic therapy. ... more      

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Title: Crisaborole (Eucrisa) for Atopic Dermatitis
Article code: 1515b
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