The Medical Letter on Drugs and Therapeutics
OTC Fluticasone Furoate Nasal Spray (Flonase Sensimist) for Allergic Rhinitis (online only)
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The nasal spray formulation of the corticosteroid fluticasone furoate is now available over the counter (OTC) as Flonase Sensimist Allergy Relief (GSK) in the same strength as the prescription product (Veramyst) for treatment of seasonal or perennial allergic rhinitis. It is the fourth intranasal corticosteroid to become available OTC.

EFFICACY — Intranasal corticosteroids are the most effective drugs available for prevention and relief of seasonal allergic rhinitis symptoms, including itching, sneezing, discharge, and congestion. They are also modestly effective in reducing ocular symptoms.1 The onset of action of intranasal corticosteroids typically occurs within 12 hours, but maximal effects may not be achieved for 7-14 days.

SAFETY — Intranasal corticosteroids can cause dryness, irritation, burning, and bleeding of the nasal ... more      

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Title: OTC Fluticasone Furoate Nasal Spray (Flonase Sensimist) for Allergic Rhinitis (online only)
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