The Medical Letter on Drugs and Therapeutics
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1521
Another Subcutaneous Immune Globulin (Cuvitru) for Primary Immunodeficiency (online only)
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The FDA has approved a subcutaneously administered 20% solution of human immune globulin (Cuvitru – Shire) for replacement therapy in patients ≥2 years old with a primary humoral immunodeficiency. Hizentra (CSL Behring), another subcutaneously administered 20% immune globulin solution, was approved in 2010 for the same indication. The IgG component of Cuvitru is similar to that of Gammagard Liquid and HyQvia, two subcutaneously administered 10% immune globulin formulations also manufactured by Shire and approved for treatment of primary immunodeficiencies.

PRIMARY IMMUNODEFICIENCIES — Primary humoral immunodeficiencies include common variable immunodeficiency (CVID), X-linked or congenital agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.1 These disorders are usually congenital, presenting in ... more      

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Title: Another Subcutaneous Immune Globulin (Cuvitru) for Primary Immunodeficiency (online only)
Article code: 1521e
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