The Medical Letter on Drugs and Therapeutics
Issue 1531
Influenza Vaccine for 2017-2018; Mavyret and Vosevi - Two New Combinations for Chronic HCV Infection; In Brief: Pancreatic Enzyme Replacement Products
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Influenza Vaccine for 2017-2018
Revised 1/26/18: In Table 2, the recommended age for Fluarix Quadrivalent was changed to ≥6 months.

Routine annual vaccination against influenza A and B viruses is recommended for everyone ≥6 months old without a specific contraindication.1

EFFECTIVENESS — The effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza illness depends on the match between the vaccine and circulating strains. Vaccine effectiveness is highest (40-60%) when the match is close, but even when the match is poor, vaccination has been shown to reduce the risk of hospitalization and death from influenza.2-4 For the 2016-2017 influenza season, the adjusted overall effectiveness of the seasonal influenza vaccine against influenza A and B viruses was 42%.5

COMPOSITION — All seasonal influenza vaccines available in the US contain the same two influenza A virus ... more      

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