The Medical Letter on Drugs and Therapeutics
Issue 1537
Antiviral Drugs for Seasonal Influenza 2017-2018; Betrixaban (Bevyxxa) for VTE Prophylaxis in Acute Medical Illness; Fiasp - Another Insulin Aspart Formulation for Diabetes; Triptorelin (Triptodur) for Central Precocious Puberty; In Brief: Pembrolizumab (Keytruda) for Cancers with Biomarkers (online only)
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Antiviral Drugs for Seasonal Influenza 2017-2018

Antiviral drugs can be used for treatment and prophylaxis of influenza. Frequently updated information on influenza activity, testing for influenza, and antiviral resistance is available from the CDC at

RECOMMENDATIONS FOR TREATMENT — The CDC recommends starting antiviral treatment as soon as possible after illness onset, without waiting for the results of influenza testing.

Antiviral treatment is recommended for all persons with suspected or confirmed influenza who have severe, complicated, or progressive illness, require hospitalization, or are at higher risk for complications, including children <5 years old (especially those <2 years old), persons <19 years old receiving long-term aspirin therapy, adults ≥65 years old, morbidly obese persons (BMI ≥40), women who are pregnant or ≤2 weeks postpartum, persons of ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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