ISSUE 1558
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The FDA has approved an over-the-counter (OTC) 0.025% ophthalmic formulation of the selective alpha2-adrenergic agonist brimonidine tartrate (Lumify – Bausch & Lomb) for treatment of ocular redness in adults and children ≥5 years old. Lumify is the first brimonidine product to be approved for OTC use.
PRESCRIPTION BRIMONIDINE PRODUCTS ― Brimonidine is available by prescription in higher-strength formulations both alone (Alphagan-P, and others) and in combinations with the beta blocker timolol (Combigan) and the carbonic anhydrase inhibitor brinzolamide (Simbrinza)1 for reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Brimonidine is also available by prescription in a topical gel formulation (Mirvaso) for treatment of the facial erythema of
... more- Brinzolamide/brimonidine (Simbrinza) for glaucoma. Med Lett Drugs Ther 2013; 55:57.
- Brimonidine gel (Mirvaso) for rosacea. Med Lett Drugs Ther 2013; 55:82.
- GL Torkildsen et al. Evaluation of efficacy and safety of brimonidine tartrate ophthalmic solution, 0.025% for treatment of ocular redness. Curr Eye Res 2018; 43:43.
- According to walgreens.com. Accessed October 11, 2018.
- E McLaurin et al. Brimonidine ophthalmic solution 0.025% for reduction of ocular redness: a randomized clinical trial. Optom Vis Sci 2018; 95:264.

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