The Medical Letter on Drugs and Therapeutics
Oral Semaglutide (Rybelsus) for Type 2 Diabetes
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An oral formulation of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide (Rybelsus – Novo Nordisk) has been approved by the FDA for once-daily treatment of type 2 diabetes in adults. Semaglutide, which has been available in a subcutaneously-injected formulation (Ozempic) since 2017, is the first GLP-1 receptor agonist to become available for oral administration; the 4 other GLP-1 receptor agonists currently available in the US are administered by subcutaneous (SC) injection. ... more
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Title: Oral Semaglutide (Rybelsus) for Type 2 Diabetes
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