Accreditation Information and Educational Objectives for Comprehensive Activities

Information about The Medical Letter CME program is available at:

The mission of The Medical Letter's Continuing Medical Education Program is to support the professional development of health care providers including physicians, nurse practitioners, pharmacists, and physician assistants by providing independent, unbiased drug information and prescribing recommendations that are free of industry influence. The program content includes current information and unbiased reviews of FDA-approved and off-label uses of drugs, their mechanisms of action, clinical trials, dosage and administration, adverse effects, and drug interactions. The Medical Letter delivers educational content in the form of self-study material.

The expected outcome of the CME Program is to increase the participant's ability to know, or apply knowledge into practice after assimilating, information presented in materials contained in The Medical Letter.

The Medical Letter will strive to continually improve the CME program through periodic assessment of the program and activities. The Medical Letter aims to be a leader in supporting the professional development of health care providers through Core Competencies by providing continuing medical education that is unbiased and free of industry influence.

The Medical Letter is supported by subscription fees and accepts no advertising.

Through this program, The Medical Letter expects to provide the health care community with unbiased, reliable, and timely educational content that they will use to make independent and informed therapeutic choices in their practice.

Activity participants will read and assimilate unbiased reviews of FDA-approved and off-label uses of drugs and other treatment modalities.

Activity participants will be able to select and prescribe, or confirm the appropriateness of the prescribed usage of, the drugs and other therapeutic modalities discussed in The Medical Letter with specific attention to clinical trials, pathophysiology, dosage and administration, drug metabolism and interactions, and patient management.

Activity participants will make independent and informed therapeutic choices in their practice.

Participants in the program have indicated their interest in this subject matter and need for information by subscribing to The Medical Letter, the content of which provides the basis for this activity. The activity is periodically evaluated, and comments and suggestions from subscribers reviewed and implemented as deemed appropriate.

The Medical Letter is an independent nonprofit organization that provides health care professionals with unbiased drug information. The Medical Letter does not sell advertising or receive any commercial support. The editorial process used for its publications relies on a review of published and unpublished literature, with an emphasis on controlled clinical trials and peer review. The questions in The Medical Letter CME Activities are designed and created by the Editorial Staff and CME Exam Committee at The Medical Letter. All individuals involved in the content on which this activity is based are required to disclose any relevant financial relationship(s) they, including spouse or partner, have with a commercial interest that benefits the individual in any financial amount that has occurred within the past 24 months. Any presenter whose disclosed relationships prove to create an irresolvable conflict of interest, with regard to their contribution to the activity, will not be permitted to present.

The Medical Letter requires that individuals responsible for the content on which a CME activity is based disclose to the audience when a conflict exists and when discussing any unlabeled or investigational use of any commercial product, or device, not yet approved for use in the United States.

The content of The Medical Letter and related CME Program is controlled by the Editor, who declares no conflict of interest.

The Medical Letter is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The Medical Letter Inc. designates this enduring material for a maximum of 26 AMA PRA Category 1 Credits(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. This CME activity was planned and produced in accordance with the ACCME Essentials and Policies.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 26 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Your participation information will be shared with ABIM through PARS.

The AAFP has reviewed The Medical Letter Continuing Education Program, and deemed it acceptable for AAFP credit. Term of approval is from 01/01/2021 to 12/31/2021. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 52 AAPA Category 1 CME credits. Approval is valid from 5/2/2021 to 12/31/2022. PAs should only claim credit commensurate with the extent of their participation. AAPA reference number: CME-202250.

Successful completion of the post-test is required to earn AAPA Category 1 CME credit. Successful completion is defined as a cumulative score of at least 70 percent correct.

The Medical Letter is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This exam is acceptable for 26.0 hour(s) of knowledge-based continuing education credit (2.6 CEU).

The American Nurses Credentialing Center (ANCC) and the American Academy of Nurse Practitioners (AANP) accept AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

This activity, being ACCME (AMA) approved, is acceptable for Category 2-B credit by the American Osteopathic Association (AOA).

Physicians in Canada: Members of The College of Family Physicians of Canada are eligible to receive Mainpro-M1 credits (equivalent to AAFP Prescribed credits) as per our reciprocal agreement with the American Academy of Family Physicians.

A score of 70% or greater is required to pass the exam. For ACPE credit, CPE Monitor ( is the only official source of credit/transcripts. Certificates/statements of credit will be emailed to those who submit and pass the exam.


Mark Abramowicz, M.D., President - The Medical Letter; has no disclosure or potential conflict of interest to report.

Jean-Marie Pflomm, Pharm.D., Editor in Chief - The Medical Letter; has no disclosure or potential conflict of interest to report.

Brinda M. Shah, Pharm.D., Consulting Editor - The Medical Letter; has no disclosure or potential conflict of interest to report.

The Medical Letter guarantees our firm commitment to your privacy. We do not sell any of your information. Secure server software (SSL) is used for commerce transactions through VeriSign, Inc. No credit card information is stored.

Windows 7/8/10, Mac OS X+; current versions of Microsoft IE/Edge, Mozilla Firefox, Google Chrome, Safari or any other compatible Web browser. High-speed connection.

For questions about this activity please call Customer Service at: (800) 211-2769.