Search Results for "apomorphine"
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Searched for apomorphine. Results 11 to 12 of 12 total matches.
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Opicapone (Ongentys) - A COMT Inhibitor for Parkinson's Disease

   
The Medical Letter on Drugs and Therapeutics • Jan 11, 2021  (Issue 1615)
) for Parkinson’s disease. Med Lett Drugs Ther 2020; 62:20. 4. Sublingual apomorphine (Kynmobi) for Parkinson’s ...
The FDA has approved opicapone (Ongentys – Neurocrine), a peripherally-acting reversible catechol-O-methyltransferase (COMT) inhibitor, for oral use as an adjunct to carbidopa/levodopa in adults with Parkinson’s disease (PD) who experience "off" episodes. It is the third COMT inhibitor to be approved for this indication; tolcapone (Tasmar, and generics) and entacapone (Comtan, and generics) were approved earlier. Opicapone has been available in Europe since 2016.
Med Lett Drugs Ther. 2021 Jan 11;63(1615):3-5 |  Show IntroductionHide Introduction

Safinamide (Xadago) for Parkinson's Disease

   
The Medical Letter on Drugs and Therapeutics • Sep 11, 2017  (Issue 1529)
. Subcutaneous apomorphine can be used for rescue treatment of “off” episodes. Deep brain stimulation ...
The FDA has approved the monoamine oxidase type B (MAO-B) inhibitor safinamide (Xadago – US Worldmeds) as an adjunct to levodopa/carbidopa for management of "off" episodes in patients with Parkinson’s disease (PD). It is the first reversible MAO-B inhibitor to be approved for this indication. Selegiline (Eldepryl, and others) and rasagiline (Azilect, and generics), two irreversible MAO-B inhibitors, have been used alone and as adjuncts to levodopa/carbidopa for many years. Safinamide is not approved for use as monotherapy.
Med Lett Drugs Ther. 2017 Sep 11;59(1529):151-3 |  Show IntroductionHide Introduction