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Eslicarbazepine Acetate (Aptiom) for Epilepsy

   
The Medical Letter on Drugs and Therapeutics • May 26, 2014  (Issue 1443)
, such as clobazam and omeprazole, and decrease serum concentrations of drugs metabolized by CYP3A4 ...
Eslicarbazepine acetate (Aptiom – Sunovion) has been approved by the FDA for adjunctive treatment of partial-onset seizures in adults. New drugs for epilepsy are often approved by the FDA initially only as adjunctive treatment for partial seizures. Eslicarbazepine acetate is a prodrug of eslicarbazepine, which is the S-isomer of the active metabolite of oxcarbazepine. Oxcarbazepine itself is similar to carbamazepine. Both oxcarbazepine and carbamazepine are available generically.
Med Lett Drugs Ther. 2014 May 26;56(1443):42-3 |  Show IntroductionHide Introduction