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See also: doxylamine, pyridoxine
Diclegis for Nausea and Vomiting of Pregnancy
The Medical Letter on Drugs and Therapeutics • Aug 05, 2013 (Issue 1422)
combination (Bendectin) for morning sickness.
Bendectin was voluntarily withdrawn in the US in
1983 because ...
The FDA has approved Diclegis (Duchesnay), a fixed-dose,
delayed-release combination of the H1-antihistamine
doxylamine and the vitamin B6 analog pyridoxine,
for treatment of nausea and vomiting of pregnancy in
women who do not respond to conservative management.
It is only available by prescription. Doxylamine
and pyridoxine, both currently available over the
counter, were previously available by prescription in a
fixed-dose combination (Bendectin) for morning sickness.
Bendectin was voluntarily withdrawn in the US in
1983 because of claims of teratogenicity that have
since been...