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See also: ganirelix acetate
Drugs for Assisted Reproduction
Treatment Guidelines from The Medical Letter • Oct 01, 2003 (Issue 14)
; Orgalutran in Canada).
Following SC injection, GnRH antagonists cause a
rapid decrease in hypothalamic ...
Infertility occurs in about 15% of couples. About one third of infertility is due to problems with ovulation or an anatomic abnormality of the fallopian tube or peritoneum, such as scarring, adhesions or endometriosis. Another third is due to a male infertility factor, most commonly insufficient sperm production or abnormal motility or morphology. The remaining third is unexplained. In older women unexplained infertility is probably caused by diminished quality and quantity of oocytes, decreased implantation and spontaneous pregnancy wastage.