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A Fixed-Dose Combination of Meloxicam and Rizatriptan (Symbravo) for Migraine

   
The Medical Letter on Drugs and Therapeutics • Apr 28, 2025  (Issue 1727)
either drug alone.3 Small-molecule calcitonin gene-related peptide (CGRP) receptor antagonists (e.g ...
The FDA has approved Symbravo (Axsome), an oral fixed-dose combination of the nonsteroidal anti-inflammatory drug (NSAID) meloxicam and the 5-HT1B/1D receptor agonist (triptan) rizatriptan (Maxalt, and generics), for acute treatment of migraine with or without aura in adults. It is the second combination of an NSAID and a triptan to be approved for migraine treatment. An oral fixed-dose combination of sumatriptan and naproxen (Treximet, and generics) is approved for use in patients ≥12 years old.
Med Lett Drugs Ther. 2025 Apr 28;67(1727):68-70   doi:10.58347/tml.2025.1727b |  Show IntroductionHide Introduction