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Penbraya: A Pentavalent Meningococcal Vaccine

   
The Medical Letter on Drugs and Therapeutics • Mar 18, 2024  (Issue 1698)
in the US with a fatality rate of 15%. Serogroup Y isolates that are penicillin- and ciprofloxacin-resistant have recently ...
The FDA has licensed Penbraya (Pfizer), a pentavalent polysaccharide conjugate meningococcal vaccine, for prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, B, C, W, or Y (MenABCWY) in persons 10-25 years old. Penbraya is the only meningococcal vaccine that contains all five of these serogroups. Two quadrivalent polysaccharide conjugate meningococcal vaccines containing serogroups A, C, W, and Y (MenACWY; Menveo, MenQuadfi) and two meningococcal serogroup B vaccines (MenB; Bexsero, Trumenba) are available in the US (see Table...
Med Lett Drugs Ther. 2024 Mar 18;66(1698):43-5   doi:10.58347/tml.2024.1698b |  Show IntroductionHide Introduction