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Searched for Comtan. Results 1 to 3 of 3 total matches.
See also: entacapone
Opicapone (Ongentys) - A COMT Inhibitor for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • Jan 11, 2021 (Issue 1615)
for this indication; tolcapone (Tasmar, and
generics) and entacapone (Comtan, and generics)
were approved earlier ...
The FDA has approved opicapone (Ongentys –
Neurocrine), a peripherally-acting reversible catechol-O-methyltransferase (COMT) inhibitor, for oral use as an
adjunct to carbidopa/levodopa in adults with Parkinson’s
disease (PD) who experience "off" episodes. It is the
third COMT inhibitor to be approved for this indication;
tolcapone (Tasmar, and generics) and entacapone
(Comtan, and generics) were approved earlier. Opicapone
has been available in Europe since 2016.
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • Feb 22, 2021 (Issue 1618)
Comtan (Novartis) 694.00
Opicapone – Ongentys (Neurocrine) 50 mg caps 50 mg PO once/day at bedtime22 ...
The motor symptoms of Parkinson's disease (PD) are
caused primarily by degeneration of dopaminergic
neurons in the substantia nigra. The nonmotor symptoms
of the disease are thought to be caused by degeneration of
other neurotransmitter systems. No disease-modifying
drugs are available for treatment of PD.
Comparison Table: Drugs for Parkinson's Disease (online only)
The Medical Letter on Drugs and Therapeutics • Feb 22, 2021 (Issue 1618)
DOSAGE1 ADMINISTRATION/COMMENTS COST2
Entacapone – generic
Comtan (Novartis)
200 mg tabs
200 mg PO tid ...
View the Comparison Table: Drugs for Parkinson's Disease