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See also: epoetin alfa

Vadadustat (Vafseo) for Anemia of Chronic Kidney Disease

   
The Medical Letter on Drugs and Therapeutics • Feb 17, 2025  (Issue 1722)
Dosage2 Cost3 Erythropoietin-Stimulating Agents (ESAs) Epoetin alfa – 50-100 units/kg IV or SC5 Procrit ...
The FDA has approved the hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) vadadustat (Vafseo – Akebia) for oral treatment of anemia due to chronic kidney disease (CKD) in adults who have been on dialysis for at least 3 months. Vadadustat is the second HIF-PHI to be approved in the US for this indication; daprodustat (Jesduvroq) was approved earlier, but it was withdrawn from the US market in 2024 for commercial reasons.
Med Lett Drugs Ther. 2025 Feb 17;67(1722):27-9   doi:10.58347/tml.2025.1722b |  Show IntroductionHide Introduction

Daprodustat (Jesduvroq) for Anemia of Chronic Kidney Disease

   
The Medical Letter on Drugs and Therapeutics • Feb 19, 2024  (Issue 1696)
agents (ESAs) Epoetin alfa – 50-100 units/kg Procrit (Janssen) IV or SC5 3x/week $1282.80 Epogen ...
The FDA has approved daprodustat (Jesduvroq – GSK), a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), for oral treatment of anemia due to chronic kidney disease (CKD) in adults who have been on dialysis for at least 4 months. It is the first HIF-PHI and the first oral drug to be approved in the US for this indication.
Med Lett Drugs Ther. 2024 Feb 19;66(1696):25-7   doi:10.58347/tml.2024.1696a |  Show IntroductionHide Introduction