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In Brief: Label Changes for Menopausal Hormone Therapy Products
The Medical Letter on Drugs and Therapeutics • Feb 16, 2026 (Issue 1748)
uterus who took oral conjugated equine estrogens
and medroxyprogesterone had an increased risk ...
The FDA has requested the removal of some boxed
warnings from the labels of vaginal and systemic
menopausal hormone therapy (MHT) products. The
warnings were initially added in 2003 based on the
results of two placebo-controlled Women's Health
Initiative (WHI) trials evaluating the use of systemic
hormones for primary prevention of coronary heart
disease (CHD) in postmenopausal women 50-79
years old.
Med Lett Drugs Ther. 2026 Feb 16;68(1748):30-1 doi:10.58347/tml.2026.1748d | Show Introduction Hide Introduction