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See also: Xyrem

Xywav - A Mixed-Salt Oxybate Oral Solution for Idiopathic Hypersomnia

   
The Medical Letter on Drugs and Therapeutics • Dec 27, 2021  (Issue 1640)
is a CNS depressant; its chemical name is gamma hydroxybutyrate (GHB), which is notorious for its use ...
Xywav (Jazz), an oral solution that contains calcium, magnesium, potassium, and sodium oxybates, has been approved by the FDA for treatment of idiopathic hypersomnia in adults. It is the first drug to be approved in the US for this indication. Xywav was approved in 2020 for treatment of excessive daytime sleepiness or cataplexy in patients ≥7 years old with narcolepsy. It contains about 92% less sodium than sodium oxybate oral solution (Xyrem), which has been available in the US for years for use in patients ≥7 years old with narcolepsy.
Med Lett Drugs Ther. 2021 Dec 27;63(1640):207-8 |  Show IntroductionHide Introduction