The Medical Letter on Drugs and Therapeutics
Addendum: Drospirenone (Slynd) - A New Progestin-Only Oral Contraceptive
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 Select a term to see related articles  Acne   Aldactone   Contraceptives   Drospirenone   Oral contraceptives   Psyllium   Slynd   Spironolactone 

In our article on Slynd (Med Lett Drugs Ther 2020; 62:18), the drospirenone-only oral contraceptive, we mentioned that drospirenone has antiandrogenic activity that could improve acne and antimineralocorticoid activity that could cause hyperkalemia. We should have added that concurrent use of drospirenone with other drugs that increase potassium levels, such as the anti-androgen aldosterone receptor antagonist spironolactone (Aldactone, and generics), which is often used off-label for treatment of acne, can increase the risk of hyperkalemia.

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