About 2.5 million persons in the US had hepatitis C between 2017 and 2020.1 Guidelines from the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) on management of hepatitis C virus (HCV) infection were updated in 2023.2
GENOTYPE PREVALENCE — About 70-75% of HCV infections in the US are caused by HCV genotype 1 (~50% are caused by genotype 1a), and about 20-25% are caused by genotype 2 or 3. HCV genotype 3 is associated with faster disease progression and increased rates of...
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RELEASE
The FDA has authorized over-the-counter (OTC) sale of a nonmedicated alcohol-based gel (Eroxon – Futura) for treatment of erectile dysfunction (ED) in males ≥22 years old. Eroxon is the only FDA-approved OTC and topical treatment for erectile dysfunction. It is also available in the UK and the EU.
STANDARD TREATMENT ― Oral phosphodiesterase type 5 (PDE5) inhibitors such as avanafil (Stendra), sildenafil (Viagra, and generics), tadalafil (Cialis, and generics), and vardenafil (Levitra, and generics) are usually tried first for treatment of ED. The onset of action is about 30-45 minutes for each of these drugs. PDE5 inhibitors can cause headache, flushing, and back pain, and they have been associated with sudden losses of vision and hearing. All PDE5 inhibitors are substrates of CYP3A4, …