The Medical Letter on Drugs and Therapeutics
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ISSUE
1070
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Entacapone for Parkinson's Disease
Entacapone (Comtan), a catechol-O-methyltransferase (COMT) inhibitor, has been approved by the FDA for adjunctive use with levodopa/carbidopa in patients with Parkinson's disease who have end-of-dose "wearing off"symptoms.
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