The Medical Letter on Drugs and Therapeutics
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In Brief: Propylthiouracil for Hyperthyroidism
The thionamides propylthiouracil and methimazole are both used to treat hyperthyroidism.1 Propylthiouracil causes severe hepatic toxicity or hepatic failure in about 0.1% of adults and children.2,3 It is the third leading cause of liver transplants...more
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