Drugs for Hypothyroidism
February 20, 2023 (Issue: 1670)
Primary hypothyroidism is usually the result of
Hashimoto's (autoimmune) thyroiditis, thyroidectomy,
or radioactive iodine therapy. Treatment of
hypothyroidism with replacement doses of thyroid
hormone is usually lifelong. Levothyroxine...more
- L Chaker et al. Hypothyroidism. Lancet 2017; 390:1550. doi:10.1016/S0140-6736(17)30703-1
- B Biondi and DS Cooper. Thyroid hormone therapy for hypothyroidism. Endocrine 2019; 66:18. doi:10.1007/s12020-019-02023-7
- JP Brito et al. Association between generic-to-generic levothyroxine switching and thyrotropin levels among US adults. JAMA Intern Med 2022; 182:418. doi:10.1001/jamainternmed.2022.0045
- E Gatta et al. Liquid levothyroxine formulations in patients taking drugs interfering with L-T4 absorption. Front Endocrinol (Lausanne) 2022; 13:1080108. doi:10.3389/fendo.2022.1080108
- J Jonklaas et al. Guidelines for the treatment of hypothyroidism: prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement. Thyroid 2014; 24:1670. doi:10.1089/thy.2014.0028
- WM Wiersinga. T4+T3 combination therapy: an unsolved problem of increasing magnitude and complexity. Endocrinol Metab (Seoul) 2021; 36:938. doi:10.3803/EnM.2021.501
- J Jonklaas et al. Evidence-based use of levothyroxine/liothyronine combinations in treating hypothyroidism: a consensus document. Thyroid 2021; 31:156. doi:10.1089/thy.2020.0720
- WM Wiersinga et al. 2012 ETA Guidelines: the use of L-T4 + L-T3 in the treatment of hypothyroidism. Eur Thyroid J 2012; 1:55. doi:10.1159/000339444
- TD Hoang et al. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. J Clin Endocrinol Metab 2013; 98:1982. doi:10.1210/jc.2012-4107
- NK Moog et al. Influence of maternal thyroid hormones during gestation on fetal brain development. Neuroscience 2017; 342:68. doi:10.1016/j.neuroscience.2015.09.070
- EK Alexander et al. 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid 2017; 27:315. doi:10.1089/thy.2016.0457
- GE Bekkering et al. Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline. BMJ 2019; 365:I2006. doi:10.1136/bmj.l2006
- B Biondi and AR Cappola. Subclinical hypothyroidism in older individuals. Lancet Diabetes Endocrinol 2022; 10:129. doi:10.1016/S2213-8587(21)00285-0
- JR Garber et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Thyroid 2012; 22:1200. doi:10.1089/thy.2012.0205
- DJ Stott et al. Thyroid hormone therapy for older adults with subclinical hypothyroidism. N Engl J Med 2017; 376:2534. doi:10.1056/NEJMoa1603825
- B Biondi et al. Subclinical hypothyroidism: a review. JAMA 2019; 322:153. doi:10.1001/jama.2019.9052
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