Treatment Guidelines from The Medical Letter
Drugs for Allergic Disorders
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The use of drugs to prevent and control symptoms of allergic disorders can be optimized when patients avoid exposure to specific allergens and/or environmental conditions that trigger or worsen their symptoms.


Allergic rhinitis can be seasonal/intermittent or perennial/ persistent. It is often associated with allergic conjunctivitis, rhinosinusitis and asthma.1,2

H1-ANTIHISTAMINES — Oral – Orally administered second-generation H1-antihistamines are the preferred first-line therapy for relief of the itching, sneezing and rhinorrhea that characterize mild to moderate allergic rhinitis. They are less effective for nasal congestion. Second-generation H1-antihistamines penetrate poorly into the central nervous system and are significantly less likely than the first-generation agents to impair CNS function and ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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