The Medical Letter on Drugs and Therapeutics
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Influenza Vaccine for 2012-2013

Annual vaccination against influenza A and B viruses is the most effective method of preventing influenza and has been shown to decrease influenza illness and its complications. A new vaccine is available for the current season. Chemoprophylaxis and treatment of influenza was discussed in an earlier issue.1

VACCINE COMPOSITION — This year’s seasonal trivalent influenza vaccine contains the following three strains: A/California/7/2009 H1N1-like (derived from the pandemic 2009 influenza virus), A/Victoria/361/2011 H3N2-like, and B/Wisconsin/1/2010-like. The H1N1 strain is the same as in last year’s vaccine. The H3N2 and B strains are new this year.2

LIVE VS. INACTIVATED VACCINE — FluMist, the intranasal live attenuated influenza vaccine (LAIV), is recommended for use only in healthy, non-pregnant persons 2-49 ... more      

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