The Medical Letter on Drugs and Therapeutics
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Influenza Vaccine for 2014-2015
Revised 11/5/2014: See Tables 1 and 2 for new age indication for FluBlok (now ≥18 years).

Annual vaccination against influenza A and B viruses has been shown to decrease influenza illness and its complications.1

EFFECTIVENESS — The effectiveness of the seasonal vaccine in preventing influenza in healthy adults depends on the match between the vaccine and circulating strains. Vaccine effectiveness is highest (50-80% in young adults; lower in the elderly) when the match is close, but even when the match is poor, vaccination has been shown to reduce the risk of death from influenza.2 In addition, vaccination of children and adolescents can protect unvaccinated residents of the same community.3

Live vs. Inactivated – The intranasal live-attenuated influenza vaccine, FluMist Quadrivalent, is only recommended for healthy, non-pregnant persons 2-49 years old. It appears ... more      

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