The Medical Letter on Drugs and Therapeutics
Exablate Neuro for Essential Tremor
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The FDA has approved use of Exablate Neuro (Insightec) for unilateral thalamotomy to treat medication-refractory essential tremor in patients ≥22 years old. Exablate Neuro uses magnetic resonance-guided focused ultrasound (MRgFUS) to create lesions in the ventral intermediate nucleus of the thalamus. MRgFUS is also approved in the US for treatment of uterine fibroids and for pain palliation of bone metastases.

TREATMENT OF ESSENTIAL TREMOR — Essential tremor is a common neurological disorder that causes involuntary and rhythmic shaking, especially of the hand, head, neck, and voice. The tremor is not life threatening, but it can be distressing and make performance of everyday activities difficult. The most effective drugs used to treat essential tremor are the beta blocker propranolol (Inderal, and others) and (off-label) the anticonvulsant primidone (Mysoline, and generics); they ... more      

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Title: Exablate Neuro for Essential Tremor
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