The Medical Letter on Drugs and Therapeutics
FROM
ISSUE 1611
ISSUE 1611
November 16, 2020
Issue 1611
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In Brief: Hydrochlorothiazide and Skin Cancer
November 16, 2020 (Issue: 1611)
The FDA has required the addition of information about
an increased risk of nonmelanoma skin cancer (basal
cell carcinoma [BCC] and squamous cell carcinoma
[SCC]) to the labels of products containing the diuretic
hydrochlorothiazide.
... more
- FDA. FDA approves label changes to hydrochlorothiazide to describe small risk of non-melanoma skin cancer. August 20, 2020. Available at: https://bit.ly/3meIjeJ. Accessed November 5, 2020.
- SA Pedersen et al. Hydrochlorothiazide use and risk of nonmelanoma skin cancer: a nationwide case-control study from Denmark. J Am Acad Dermatol 2018; 78:673.
- E Eworuke et al. Risk of non-melanoma skin cancer associated with hydrochlorothiazide-containing products in the United States. International Conference on Pharmacoepidemiology & Therapeutic Risk Management. Virtual event. September 16-17, 2020. Available at: https://bit.ly/3eqHHQy. Accessed November 5, 2020.
- AØ Jensen et al. Use of photosensitising diuretics and risk of skin cancer: a population-based case-control study. Br J Cancer 2008; 99:1522.
- Sunscreens. Med Lett Drugs Ther 2018; 60:129.

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