Search Results for "Chemotherapy"
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Searched for Chemotherapy. Results 121 to 130 of 220 total matches.
In Brief: Asparaginase Erwinia chrysanthemi (Erwinaze) for ALL
The Medical Letter on Drugs and Therapeutics • Apr 16, 2012 (Issue 1388)
of childhood. Multidrug
chemotherapy can cure about 80% of children with ALL.1
Initial treatment (“induction ...
The FDA has approved asparaginase Erwinia chrysanthemi (Erwinaze – EUSA), an asparagine-specific enzyme derived from the gram-negative bacillus Erwinia chrysanthemi, for use in combination with other chemotherapeutic agents for treatment of acute lymphoblastic leukemia (ALL) in patients who have had allergic reactions to Escherichia coli-derived asparaginase (Elspar or pegaspargase [Oncaspar]).ALL is the most common malignancy of childhood. Multidrug chemotherapy can cure about 80% of children with ALL.1 Initial treatment ("induction") usually includes vincristine, a glucocorticoid, and an...
Two New Drugs for Colon Cancer
The Medical Letter on Drugs and Therapeutics • Jun 07, 2004 (Issue 1184)
colorectal cancer that had progressed despite treatment with an irinotecanbased chemotherapy regimen were ...
Cetuximab (Erbitux - ImClone Systems/Bristol-Myers Squibb), an epidermal growth factor receptor (EGFR) inhibitor, and bevacizumab (Avastin - Genentech), the first vascular endothelial growth factor angiogenesis inhibitor, have recently been approved by the FDA for treatment of patients with metastatic colorectal cancer. Cetuximab is approved for treatment of patients with EGFR-expressing tumors, either in combination regimens with irinotecan (Camptosar)when the cancer has progressed on irinotecan-based therapy, or as monotherapy for those who cannot tolerate irinotecan. Bevacizumab is approved...
Acupuncture
The Medical Letter on Drugs and Therapeutics • May 08, 2006 (Issue 1234)
Palliative Care – In one meta-analysis,
acupuncture, particularly electroacupuncture,
reduced chemotherapy ...
Acupuncture is the practice of inserting fine needles for therapeutic purposes into points on the skin known as acupoints. In traditional Chinese medicine theory, these points arefound along channels that conduct "qi" (pronounced "chee"), or energy. In addition to insertion of needles, acupoints can be stimulated by heat, electrical current or just pressure.
Toremifene and Letrozole for Advanced Breast Cancer
The Medical Letter on Drugs and Therapeutics • Apr 10, 1998 (Issue 1024)
OR COPYING IS A VIOLATION OF U.S. AND INTERNATIONAL COPYRIGHT LAWS
Cancer chemotherapy letrozole for breast ...
The antiestrogen toremifene (Fareston - Schering) and the selective aromatase inhibitor letrozole (Femara - Novartis) have been approved by the FDA for treatment of advanced breast cancer in postmenopausal women.
Two Drugs for RET-Altered Cancers (Retevmo and Gavreto) (online only)
The Medical Letter on Drugs and Therapeutics • Jul 10, 2023 (Issue 1680)
chemotherapy. The median duration of response was
not yet reached in treatment-naive patients and 17.5
months ...
The oral kinase inhibitors selpercatinib (Retevmo –
Lilly) and pralsetinib (Gavreto – Blueprint Medicines/Genentech) have been approved by the FDA for
treatment of advanced or metastatic RET-mutant
or RET fusion-positive cancers. They are the first
drugs to be approved specifically for certain RET-driven
cancers. Both drugs were granted accelerated
approval based on overall response rates and the
duration of response.
Med Lett Drugs Ther. 2023 Jul 10;65(1680):e120-1 doi:10.58347/tml.2023.1680e | Show Introduction Hide Introduction
Repotrectinib (Augtyro) for Non-Small Cell Lung Cancer (online only)
The Medical Letter on Drugs and Therapeutics • Feb 19, 2024 (Issue 1696)
of platinum-based chemotherapy and/
or immunotherapy, but not tyrosine kinase inhibitor
therapy, the overall ...
The FDA has approved the oral tyrosine kinase
inhibitor repotrectinib (Augtyro – BMS) for treatment
of locally advanced or metastatic ROS1-positive
non-small cell lung cancer (NSCLC) in adults.
Repotrectinib is the third oral tyrosine kinase inhibitor
to be approved for this indication in the US; crizotinib
(Xalkori) and entrectinib (Rozlytrek) were approved
earlier.
Med Lett Drugs Ther. 2024 Feb 19;66(1696):e36-7 doi:10.58347/tml.2024.1696g | Show Introduction Hide Introduction
In Brief: Dinutuximab (Unituxin) for High-Risk Neuroblastoma (online only)
The Medical Letter on Drugs and Therapeutics • Mar 28, 2016 (Issue 1491)
that had at least a partial response
to induction chemotherapy, autologous stem cell
transplantation ...
The FDA has approved use of dinutuximab (Unituxin [yoo ni tux' in] – United Therapeutics) in combination with interleukin-2 (IL-2), granulocyte-macrophage colony-stimulating factor (GM-CSF), and isotretinoin for treatment of children with high-risk neuroblastoma who previously responded to first-line therapies. Dinutuximab is a monoclonal antibody that binds to GD2, a glycolipid that is overexpressed on the surface of neuroblastoma cells.1Dinutuximab received a priority review and orphan drug designation. Approval was based on the results of an open-label trial in 226 patients with high-risk...
Mitomycin Solution (Mitosol) for Glaucoma Surgery
The Medical Letter on Drugs and Therapeutics • Mar 18, 2013 (Issue 1412)
for reconstitution, sponges, a
chemotherapy waste bag and instructions for use. One
kit costs $359.3
CONCLUSION ...
A topical formulation of the antimetabolite mitomycin
(Mitosol – Mobius Therapeutics) has been approved by
the FDA for adjunctive use in glaucoma surgery to
reduce scarring. Compounding pharmacies have supplied
the drug off-label for this purpose for many years.
Mitoxantrone
The Medical Letter on Drugs and Therapeutics • Jul 01, 1988 (Issue 769)
, with or without previous chemotherapy, with 35% to 57% response rates
reported, similar to rates with combination ...
Mitoxantrone (Novantrone - Lederle), a synthetic anthracene related to the anthracyclines doxorubicin (Adriamycin) and daunorubicin (Cerubidine), has now been marketed in the USA to be used in combination with other drugs for initial treatment of acute nonlymphocytic leukemia in adults.
Doripenem (Doribax) - A New Parenteral Carbapenem
The Medical Letter on Drugs and Therapeutics • Jan 28, 2008 (Issue 1278)
. 46th
Interscience Conference on Antimicrobial Agents and
Chemotherapy; San Francisco, CA; September ...
Doripenem (Doribax - Ortho-McNeil Janssen), an intravenous (IV) carbapenem antibiotic with a spectrum of activity similar to that of imipenem and meropenem, has been approved by the FDA for treatment of complicated intra-abdominal and urinary tract infections. Use of doripenem for treatment of nosocomial pneumonia, including ventilator-associated pneumonia, is still under FDA review.