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Searched for 1. Results 1891 to 1900 of 2621 total matches.
Fluvastatin for Lowering Cholesterol
The Medical Letter on Drugs and Therapeutics • May 27, 1994 (Issue 923)
an additional 8% decrease in LDL (DL Sprecher et al, Ann
Intern Med, 120:537, April 1, 1994). No studies ...
Fluvastatin (Lescol - Sandoz), an HMG-CoA reductase inhibitor, was recently marketed in the USA for treatment of hypercholesterolemia. A synthetic mevalonolactone derivative, it is chemically distinct from previously available drugs in this class.
Tacrolimus FK506 Organ Transplants
The Medical Letter on Drugs and Therapeutics • Sep 16, 1994 (Issue 931)
of acute rejection
than patients treated with cyclosporine (41% vs 50%) and fewer refractory rejections (1 ...
Tacrolimus (Prograf - Fujisawa), previously called FK506 (Medical Letter, 33:94, 1991), has been approved by the US Food and Drug Administration for primary prevention of organ rejection in patients receiving liver transplants. The drug has also been used as rescue therapy for organ graft rejection unresponsive to cyclosporine (Sandimmune) and other immunosuppressive drugs.
Cefepime (Maxipime) - A New Parenteral Cephalosporin
The Medical Letter on Drugs and Therapeutics • Sep 13, 1996 (Issue 983)
) 35.69 1 gram q12h 71.38
Imipenem-cilastatin (Primaxin) 50.04 500 mg/500 mg q6h 100.08
* Cost ...
Cefepime hydrochloride (Maxipime - Bristol-Myers Squibb), a new 'fourth-generation' cephalosporin, has been approved by the US Food and Drug Administration (FDA) for parenteral treatment of urinary tract infections and skin and skin-structure infections due to susceptible pathogens, and for moderate to severe pneunmonia caused by Streptococcus pneumoniae (pneumococci), Pseudomonas aeruginosa, Enterobacter or Klebsiella pneumoniae.
Grepafloxacin--A New Fluoroquinolone
The Medical Letter on Drugs and Therapeutics • Jan 30, 1998 (Issue 1019)
Cost*
500 mg on day 1, then 250 mg qd
x 4 days
Azithromycin − Zithromax (Pfizer) $ 37.31
Cefuroxime ...
Grepafloxacin (Raxar - Glaxo Wellcome), a once-daily oral fluoroquinolone, is now being marketed for treatment of community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, uncomplicated gonorrhea, and nongonococcal urethritis and cervicitis.
Creatine and Androstenedione--Two "Dietary Supplements"
The Medical Letter on Drugs and Therapeutics • Nov 06, 1998 (Issue 1039)
. The primary food sources for creatine are meat and fish; the usual diet
in the USA provides about 1 to 2 ...
Creatine, a natural amino acid derivative, and androstenedione, a testosterone precursor, are marketed as 'dietary supplements' in health food stores and are widely believed to enhance athletic performance. Both have been in the news recently because Mark McGwire, the baseball home-run record-setter, reportedly has said he takes both. Neither has been approved for any indication by the US Food and Drug Administration (FDA).
Modafinil for Narcolepsy
The Medical Letter on Drugs and Therapeutics • Mar 26, 1999 (Issue 1049)
in animals without causing agitation. Even though modafinil is
not an α
1
-adrenergic agonist, centrally ...
Modafinil (Provigil), a benzhydryl sulfinylacetamide non-amphetamine stimulant that has been used in Europe since 1995, has now been approved by the FDA for treatment of excessive daytime sleepiness associated with narcolepsy.
Quinupristin/Dalfopristin
The Medical Letter on Drugs and Therapeutics • Nov 19, 1999 (Issue 1066)
and -resistant Streptococcus pneumoniae (RG Finch, Drugs, 51 suppl 1:31, 1996). It also is active in vitro ...
Quinupristin and dalfopristin, two streptogramin antibacterials marketed in a 30:70 combination as Synercid, have received accelerated approval from the FDA for intravenous treatment of bacteremia and life-threatening infection....
Fluoxetine Sarafem For Premenstrual Dysphoric Disorder
The Medical Letter on Drugs and Therapeutics • Jan 22, 2001 (Issue 1096)
Halbreich et al and EW Freeman et al, Int J Neuropsychopharmacol July 2000;
3 suppl 1:S248 and S241 ...
Fluoxetine, a selective serotonin reuptake inhibitor (SSRI) previously sold only as Prozac, is now also marketed as Sarafem for treatment of premenstrual dysphoric disorder (PMDD). Generic fluoxetine is expected to be available sometime this year.
A New Snake Antivenom
The Medical Letter on Drugs and Therapeutics • Jun 25, 2001 (Issue 1107)
is available from Savage Laboratories (1-800-2310206). The cost of 12 vials would be $9,300. Although ...
CroFab, an antigen-binding-fragment (Fab) antivenom of ovine origin, has been approved by the FDA for treatment of North American rattlesnake envenomation.
Zoledronate (Zometa)
The Medical Letter on Drugs and Therapeutics • Dec 10, 2001 (Issue 1120)
%) (JP Brown et al, J Bone Miner Res 2001; 16 suppl
1:S218, abstract F353).
ADVERSE EFFECTS — Adverse ...
Zoledronic acid (Zometa), a new bisphosphonate, has been approved by the FDA for intravenous (IV) treatment of hypercalcemia of malignancy.