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Searched for worsen. Results 71 to 80 of 161 total matches.
Glucagon Nasal Powder (Baqsimi) for Severe Hypoglycemia
The Medical Letter on Drugs and Therapeutics • Sep 23, 2019 (Issue 1581)
;
worsening of hypoglycemia has been reported.
PREGNANCY AND LACTATION – Glucagon has not
been associated ...
The FDA has approved glucagon nasal powder
(Baqsimi – Lilly) for treatment of severe hypoglycemia
in patients ≥4 years old with diabetes. Baqsimi is the
first noninjectable glucagon formulation to become
available in the US. Injectable glucagon emergency kits
(GlucaGen Hypokit, and generic) have been available
for years, but they require reconstitution of the
lyophilized powder by the caregiver immediately before
injection. An injectable glucagon formulation that does
not require reconstitution was recently approved by the
FDA (Gvoke) and is expected to become available...
Fenoldopam--A New Drug for Parenteral Treatment of Severe Hypertension
The Medical Letter on Drugs and Therapeutics • May 22, 1998 (Issue 1027)
). With its natriuretic/diuretic properties, fenoldopam
could worsen volume depletion in some patients ...
Fenoldopam mesylte (Corlopam - Neurex), a peripheral dopamine-1 (DA1) agonist, has been approved by the FDA for parenteral use in lowering blood pressure. The manufacturer claims that, unlike other parenteral antihypertensive agents, fenoldopam not only lowers blood pressure but also maintains or improves renal function.
Entecavir (Baraclude) for Chronic Hepatitis B
The Medical Letter on Drugs and Therapeutics • Jun 06, 2005 (Issue 1210)
with no worsening in Knodell Fibrosis Score at week 48.
2. Undetectable HBV DNA = ...
Entecavir (Baraclude - Bristol-Myers Squibb), a nucleoside analog, has been approved by the FDA for treatment of adults with active chronic hepatitis B virus (HBV) infection.
Nifurtimox (Lampit) for Chagas Disease (online only)
The Medical Letter on Drugs and Therapeutics • Jul 22, 2024 (Issue 1707)
,
carcinogenicity, mutagenicity, worsening of
neurological conditions, paresthesia, hypersensitivity,
vertigo ...
The FDA has approved the nitrofuran antiprotozoal drug
nifurtimox (Lampit – Bayer) for treatment of Chagas
disease (American trypanosomiasis) in children who
weigh ≥2.5 kg. Nifurtimox was previously available in
the US only through a CDC-sponsored Investigational
New Drug (IND) program.
Med Lett Drugs Ther. 2024 Jul 22;66(1707):e123-4 doi:10.58347/tml.2024.1707h | Show Introduction Hide Introduction
Tirzepatide (Zepbound) for Obstructive Sleep Apnea
The Medical Letter on Drugs and Therapeutics • Feb 17, 2025 (Issue 1722)
with other weight-loss
drugs; patients should be monitored for worsening
depression and suicidal thoughts ...
The injectable glucose-dependent insulinotropic
polypeptide (GIP)/glucagon-like peptide-1 (GLP-1)
receptor agonist tirzepatide (Zepbound) has been
approved by the FDA for treatment of moderate to
severe obstructive sleep apnea (OSA) in adults with
obesity. It is the first drug to be approved in the US for
this indication. Zepbound is also approved for chronic
weight management in adults with obesity and in those
who are overweight and have at least one weightrelated
comorbidity. Tirzepatide is also available as
Mounjaro for treatment of type 2 diabetes.
Med Lett Drugs Ther. 2025 Feb 17;67(1722):29-31 doi:10.58347/tml.2025.1722c | Show Introduction Hide Introduction
Miudella – A Lower-Dose Copper IUD
The Medical Letter on Drugs and Therapeutics • Apr 28, 2025 (Issue 5106)
worsen
symptoms of the disease).
CONCLUSION — Miudella, a new copper intrauterine
device (IUD ...
Miudella (Sebela), a copper intrauterine device (IUD),
has been approved by the FDA for prevention of
pregnancy for up to 3 years. Miudella is the second
copper IUD to be approved in the US; ParaGard, which
contains more copper and is approved for up to 10
years of use, was approved in 1984. Four hormonal
IUDs (Mirena, Liletta, Skyla, Kyleena) that release
the progestin levonorgestrel are also available for
pregnancy prevention (see Table 2).
Med Lett Drugs Ther. 2025 Apr 28;67(5106):1-2 doi:10.58347/tml.2025.5106a | Show Introduction Hide Introduction
Diclofenac
The Medical Letter on Drugs and Therapeutics • Dec 02, 1988 (Issue 780)
thereafter, and
discontinuing the drug if abnormalities persist or worsen (EG Breen et al, Gut, 27:1390 ...
Diclofenac sodium (Voltaren - Geigy), a nonsteroidal anti-inflammatory drug (NSAID) available in some countries since 1974, was recently introduced in the USA for treatment of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It is being promoted as 'The number one prescribed antiarthritic in the world.'
Aspirin For Prevention Of Myocardial Infarction And Stroke
The Medical Letter on Drugs and Therapeutics • Aug 25, 1989 (Issue 799)
recurrence or worsening of cardiovascular disease has become a
common practice in recent years (Medical ...
Taking aspirin to prevent recurrence or worsening of cardiovascular disease has become a common practice in recent years (Medical Letter, 28:31, 1986). Now, the US Food and Drug Administration is considering whether aspirin can also be advertised for prevention of a first myocardial infarction in previously healthy people.
Ramucirumab (Cyramza) for Gastric and GEJ Cancer (online only)
The Medical Letter on Drugs and Therapeutics • May 11, 2015 (Issue 1468)
thromboembolic events, and gastrointestinal
perforation, and can impair wound healing. New onset
or worsening ...
Ramucirumab (Cyramza – Lilly), a monoclonal antibody
that inhibits vascular endothelial growth factor
receptor 2 (VEGFR2), has been approved by the FDA for
use as monotherapy or in combination with paclitaxel
for treatment of advanced or metastatic gastric or
gastroesophageal junction (GEJ) adenocarcinoma
that has progressed on or after platinum- or
fluoropyrimidine-based chemotherapy. Ramucirumab
is also approved for use in combination with docetaxel
(Taxotere, and others) for treatment of metastatic
non-small cell lung cancer that has progressed on or
after platinum-based...
Transdermal Fentanyl (Ionsys) for Postoperative Pain
The Medical Letter on Drugs and Therapeutics • Nov 09, 2015 (Issue 1481)
disorders, or bradyarrhythmias should
be monitored for worsening symptoms.
156
The Medical Letter ® Vol ...
A patient-controlled fentanyl iontophoretic transdermal
system (Ionsys – The Medicines Company)
is now available for short-term management of acute
postoperative pain in adults requiring opioid analgesia
in the hospital. Before using Ionsys, patients must
be titrated to a comfortable level of analgesia with
another opioid formulation.