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See also: phendimetrazine

Contrave - A Combination of Bupropion and Naltrexone for Weight Loss

   
The Medical Letter on Drugs and Therapeutics • Nov 10, 2014  (Issue 1455)
Phendimetrazine – generic 35 mg tabs 35 mg bid to 70 mg tid 22.50 Bontril PDM (Valeant) 50.90 Phentermine ...
The FDA has approved a fixed-dose combination of the opioid receptor antagonist naltrexone (ReVia, and others) and the antidepressant and smoking cessation agent bupropion (Wellbutrin SR, Zyban, and others), as Contrave (Orexigen/Takeda) for weight loss. The combination was approved for use as an adjunct to diet and increased physical activity in patients with a body mass index (BMI) ≥30 kg/m2 or a BMI ≥27 kg/m2 and one or more weight-related comorbidities such as hypertension, diabetes, or dyslipidemia. Naltrexone/bupropion is not a controlled...
Med Lett Drugs Ther. 2014 Nov 10;56(1455):112-4 |  Show IntroductionHide Introduction

Two Drugs for Weight Loss

   
The Medical Letter on Drugs and Therapeutics • Sep 03, 2012  (Issue 1398)
tabs 25 mg tid or 19.80 75 mg once Phendimetrazine – generic 35 mg tabs 35 mg bid 8.40 Bontril PDM ...
In 2013 the FDA approved one new drug and a new combination of 2 old drugs as adjuncts to lifestyle changes for chronic weight management. Lorcaserin (lor-ca-SER-in; Belviq – Arena/Esai) is a selective serotonin 2C receptor agonist. Qsymia (Vivus) is a fixed-dose combination of the weight-loss drug phentermine and an extended-release (ER) formulation of topiramate. The new products are approved for use in obese patients (body mass index [BMI] of ≥30 kg/m2) and for patients who are overweight (BMI ≥27 kg/m2) and have one weight-related risk factor such as hypertension, dyslipidemia or...
Med Lett Drugs Ther. 2012 Sep 3;54(1398):69-71 |  Show IntroductionHide Introduction