Search Results for "Pain"
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Searched for Pain. Results 1 to 10 of 271 total matches.
Opioids for Pain
The Medical Letter on Drugs and Therapeutics • Dec 12, 2022 (Issue 1665)
Opioids for Pain ...
A new CDC guideline for prescribing opioids for pain
recently became available. Nonopioid drugs for pain
were reviewed in a previous issue.
Nonopioid Drugs for Pain
The Medical Letter on Drugs and Therapeutics • Mar 07, 2022 (Issue 1645)
Nonopioid Drugs for Pain ...
Nonopioid drugs can be used in the treatment of
many nociceptive and neuropathic pain conditions.
For severe pain, especially severe chronic cancer
pain, use of opioids may be necessary. Noninvasive
nonpharmacologic treatments, including physical
and psychological therapies, have been shown to
improve pain and function in patients with some
common chronic pain conditions and are unlikely
to cause serious harms. A multimodal approach to
analgesic therapy can increase pain control while
reducing opioid use and adverse effects.
Tramadol/Celecoxib (Seglentis) for Pain
The Medical Letter on Drugs and Therapeutics • Apr 18, 2022 (Issue 1648)
Tramadol/Celecoxib (Seglentis) for Pain ...
The FDA has approved Seglentis (Esteve/Kowa), an
oral combination of tramadol hydrochloride, a weak
opioid agonist and weak serotonin and norepinephrine
reuptake inhibitor (SNRI), and celecoxib, a COX-2
selective nonsteroidal anti-inflammatory drug
(NSAID), for use in adults with acute pain that is
severe enough to require an opioid and for which
alternative treatment options are inadequate.
Bupivacaine/Meloxicam (Zynrelef) for Postsurgical Pain
The Medical Letter on Drugs and Therapeutics • Jan 24, 2022 (Issue 1642)
Bupivacaine/Meloxicam (Zynrelef) for Postsurgical Pain ...
The FDA has approved a fixed-dose combination
of the amide local anesthetic bupivacaine and
the nonsteroidal anti-inflammatory drug (NSAID)
meloxicam as an extended-release (ER) solution
(Zynrelef – Heron) for single-dose, intraoperative,
soft-tissue or periarticular instillation to provide
postsurgical analgesia for up to 72 hours in adults
undergoing foot and ankle, small-to-medium open
abdominal, or lower extremity total joint arthroplasty
surgical procedures.
Tramadol Oral Solution (Qdolo) for Pain
The Medical Letter on Drugs and Therapeutics • May 31, 2021 (Issue 1625)
Tramadol Oral Solution (Qdolo) for Pain ...
The opioid agonist tramadol is now available in an oral
solution (Qdolo – Athena Bioscience) for management
of pain severe enough to require an opioid and for
which alternative treatment options are inadequate.
Tramadol has been available for years in immediate-release
tablets and capsules, extended-release
capsules (Ultram, and others), and in a fixed-dose
combination tablet with acetaminophen (Ultracet,
and generics).
Oliceridine (Olinvyk) - A New Opioid for Severe Pain
The Medical Letter on Drugs and Therapeutics • Mar 08, 2021 (Issue 1619)
Oliceridine (Olinvyk) - A New Opioid for Severe Pain ...
Oliceridine (Olinvyk - Trevena), an IV opioid agonist,
has been approved by the FDA for management of
acute pain severe enough to require an opioid and for
which alternative treatment options are inadequate.
Suzetrigine (Journavx) — A Sodium Channel Blocker for Acute Pain
The Medical Letter on Drugs and Therapeutics • Mar 03, 2025 (Issue 1723)
Suzetrigine (Journavx) — A Sodium Channel Blocker for Acute Pain ...
The FDA has approved suzetrigine (Journavx –
Vertex), a selective sodium channel blocker, for oral
treatment of moderate to severe acute pain in adults.
Suzetrigine is the first sodium channel blocker to be
approved in the US for this indication and the first oral
nonopioid drug to be approved for treatment of pain
in over 25 years.
Med Lett Drugs Ther. 2025 Mar 3;67(1723):33-5 doi:10.58347/tml.2025.1723a | Show Introduction Hide Introduction
Comparison Table: Some Nonopioid Analgesics for Pain (online only)
The Medical Letter on Drugs and Therapeutics • Mar 07, 2022 (Issue 1645)
Comparison Table: Some Nonopioid Analgesics for Pain (online only) ...
View the Comparison Table: Some Nonopioid Analgesics for Pain
Comparison Chart: Some Drugs for Abdominal Pain in Irritable Bowel Syndrome (IBS) (online only)
The Medical Letter on Drugs and Therapeutics • Feb 03, 2025 (Issue 1721)
Comparison Chart: Some Drugs for Abdominal Pain in Irritable Bowel Syndrome (IBS) (online only) ...
View the Comparison Chart: Some Drugs for Abdominal Pain in Irritable Bowel Syndrome (IBS)
Med Lett Drugs Ther. 2025 Feb 3;67(1721):e1-2 doi:10.58347/tml.2025.1721d | Show Introduction Hide Introduction
Orphengesic Forte - An Old Analgesic Combination Returns
The Medical Letter on Drugs and Therapeutics • Nov 16, 2020 (Issue 1611)
as a prescription drug by the FDA for treatment of mild to moderate pain caused by acute musculoskeletal disorders ...
A fixed-dose combination of orphenadrine citrate, aspirin,
and caffeine (Orphengesic Forte – Galt; previously
available as Norgesic Forte) has been approved as
a prescription drug by the FDA for treatment of mild
to moderate pain caused by acute musculoskeletal
disorders. Single-ingredient generic orphenadrine
citrate is available by prescription in oral and injectable
formulations and has been used for years as an adjunct
for treatment of acute musculoskeletal pain. Orphengesic
Forte is being marketed as a non-opioid alternative for
pain relief.