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Searched for gestodene. Results 1 to 2 of 2 total matches.

Topical Roflumilast (Zoryve) for Plaque Psoriasis

   
The Medical Letter on Drugs and Therapeutics • Jan 23, 2023  (Issue 1668)
and the synthetic progestin gestodene increased systemic exposure of oral roflumilast. DOSAGE AND ADMINISTRATION ...
The FDA has approved a 0.3% cream formulation of the phosphodiesterase-4 (PDE4) inhibitor roflumilast (Zoryve – Arcutis) for topical treatment of plaque psoriasis in patients ≥12 years old. Roflumilast is the first topical PDE4 inhibitor to be approved by the FDA for this indication; crisaborole (Eucrisa), another topical PDE4 inhibitor, is approved for treatment of atopic dermatitis. Oral roflumilast (Daliresp) is approved for treatment of chronic obstructive pulmonary disease.
Med Lett Drugs Ther. 2023 Jan 23;65(1668):10-2   doi:10.58347/tml.2023.1668b |  Show IntroductionHide Introduction

Roflumilast Foam (Zoryve) for Seborrheic Dermatitis

   
The Medical Letter on Drugs and Therapeutics • Apr 15, 2024  (Issue 1700)
In a pharmacokinetic study, coadministration of ethinyl estradiol and the synthetic progestin gestodene increased ...
The FDA has approved a 0.3% foam formulation of the phosphodiesterase-4 (PDE4) inhibitor roflumilast (Zoryve – Arcutis) for topical treatment of seborrheic dermatitis in patients ≥9 years old. Roflumilast is the first PDE4 inhibitor to be approved in the US for this indication. It is also available in a 0.3% cream formulation (Zoryve) for treatment of plaque psoriasis and in an oral formulation (Daliresp, and generics) for treatment of chronic obstructive pulmonary disease. A 0.15% cream formulation for treatment of atopic dermatitis in patients ≥6 years old will be reviewed...
Med Lett Drugs Ther. 2024 Apr 15;66(1700):57-9   doi:10.58347/tml.2024.1700a |  Show IntroductionHide Introduction