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Bexagliflozin (Brenzavvy) — A Fifth SGLT2 Inhibitor for Type 2 Diabetes
The Medical Letter on Drugs and Therapeutics • Aug 21, 2023 (Issue 1683)
, the sulfonylurea glimepiride (Amaryl,
and generics), or the dipeptidyl peptidase-4 (DPPTable
2. Some ...
Bexagliflozin (Brenzavvy – TheracosBio), a sodium-glucose
cotransporter 2 (SGLT2) inhibitor, has been
approved by the FDA to improve glycemic control
in adults with type 2 diabetes. It is the fifth SGLT2
inhibitor to be approved in the US for this indication
(see Table 4).
Med Lett Drugs Ther. 2023 Aug 21;65(1683):130-2 doi:10.58347/tml.2023.1683b | Show Introduction Hide Introduction
Drugs for Type 2 Diabetes
The Medical Letter on Drugs and Therapeutics • Nov 14, 2022 (Issue 1663)
glimepiride, the GLP-1 receptor agonist liraglutide, and
the DDP-4 inhibitor sitagliptin) added to metformin ...
Diet, exercise, and weight loss can improve glycemic
control, but almost all patients with type 2 diabetes
require antihyperglycemic drug therapy. Treating to
a target A1C of <7% while minimizing hypoglycemia
is recommended to prevent microvascular complications
of diabetes (retinopathy, nephropathy, and
neuropathy). An A1C target of <8% may be appropriate
for some older patients.