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See also: Intron A
In Brief: Adstiladrin – A Gene Therapy for Bladder Cancer (online only)
The Medical Letter on Drugs and Therapeutics • Mar 06, 2023 (Issue 1671)
interferon-alfa 2b to the bladder epithelium,
where it has anti-tumor effects. Syn3, a polyamide
surfactant ...
Nadofaragene firadenovec-vncg (Adstiladrin – Ferring), an adenoviral vector-based gene therapy,
has been approved by the FDA for treatment of adults
with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer
(NMIBC) with carcinoma in situ with or without
papillary tumors. It is the first adenoviral vector-based
gene therapy to be approved in the US for
this indication. The immune checkpoint inhibitor
pembrolizumab (Keytruda) was approved for the
same indication in 2021.
Med Lett Drugs Ther. 2023 Mar 6;65(1671):e40-1 doi:10.58347/tml.2023.1671e | Show Introduction Hide Introduction