View the Comparison Table: Some Lipid-Lowering Drugs

The FDA has approved evinacumab-dgnb (Evkeeza – Regeneron), an angiopoietin-like 3 (ANGPTL3) inhibitor, for adjunctive IV treatment of homozygous familial hypercholesterolemia (HoFH) in patients ≥12 years old. Evinacumab is the first ANGPTL3 inhibitor to be approved in the US.

The lipid-lowering drug rosuvastatin is now available in a sprinkle capsule formulation (Ezallor Sprinkle – Sun Pharma). Rosuvastatin tablets (Crestor, and generics) have been available since 2003.1,2

The new formulation is being marketed specifically for residents of long-term care facilities who have difficulty swallowing. Ezallor Sprinkle capsules can be swallowed whole or opened and their contents sprinkled over applesauce or mixed with water for administration via nasogastric tube.

For those long-term care residents who still have a reasonable indication for a statin but have difficulty swallowing whole tablets, crushing generic rosuvastatin tablets would be a much less expensive option.

Expanded Table: Statins

1. Rosuvastatin – a new lipid-lowering drug. Med Lett Drugs Ther 2003; 45:81
2. Lipid-lowering drugs. Med Lett Drugs Ther 2019; 61:17.

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View the Expanded Table: Statins