Search Results for "Chemotherapy"
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Searched for Chemotherapy. Results 111 to 120 of 220 total matches.

Carboplatin

   
The Medical Letter on Drugs and Therapeutics • Sep 08, 1989  (Issue 800)
and generally less toxic than cisplatin for initial chemotherapy of ovarian cancer. THE MEDICAL LETTER (ISSN ...
Carboplatin (Paraplatin - Bristol-Myers), a cytotoxic platinum-containing drug chemically related to cisplatin (Platinol), was recently approved by the US Food and Drug Administration (FDA) for palliative treatment of patients with recurrent ovarian cancer, including those previously treated with cisplatin.
Med Lett Drugs Ther. 1989 Sep 8;31(800):83-4 |  Show IntroductionHide Introduction

Futibatinib (Lytgobi) for Cholangiocarcinoma (online only)

   
The Medical Letter on Drugs and Therapeutics • Apr 17, 2023  (Issue 1674)
Canc Netw 2019; 17:302. 6. MA Lowery et al. Second-line chemotherapy in advanced biliary cancers ...
The oral kinase inhibitor futibatinib (Lytgobi – Taiho) has received accelerated approval from the FDA for treatment of adults with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma with fibroblast growth factor receptor 2 (FGFR2) fusions or other rearrangements. Accelerated approval was based on the overall response rate and duration of response. Futibatinib is the second drug to be approved for this indication; pemigatinib (Pemazyre) was approved earlier.
Med Lett Drugs Ther. 2023 Apr 17;65(1674):e69-70   doi:10.58347/tml.2023.1674f |  Show IntroductionHide Introduction

Abemaciclib (Verzenio) - A Third CDK 4/6 Inhibitor for Breast Cancer

   
The Medical Letter on Drugs and Therapeutics • Nov 06, 2017  (Issue 1533)
or two chemotherapy regimens for metastatic disease received abemaciclib monotherapy. At 12 months ...
The FDA has approved abemaciclib (Verzenio – Lilly), an oral cyclin-dependent kinase (CDK) 4/6 inhibitor, for treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer. Abemaciclib is the third CDK 4/6 inhibitor to be approved in the US for this indication.
Med Lett Drugs Ther. 2017 Nov 6;59(1533):185-6 |  Show IntroductionHide Introduction

Rasburicase (Elitek) for Hyperuricemia

   
The Medical Letter on Drugs and Therapeutics • Nov 11, 2002  (Issue 1143)
high risk, either from rapid turnover of the cancer or from the first course of chemotherapy ...
Rasburicase (Elitek - Sanofi-Synthelabo), a recombinant form of urate oxidase derived from the fungus Aspergillus flavus, has been approved by the FDA for intravenous (IV) management of hyperuricemia associated with tumor lysis syndrome in pediatric patients.
Med Lett Drugs Ther. 2002 Nov 11;44(1143):96-7 |  Show IntroductionHide Introduction

Beta-Adrenergic Blockers and Breast Cancer

   
The Medical Letter on Drugs and Therapeutics • Jan 23, 2012  (Issue 1382)
blocker at the start of neoadjuvant chemotherapy was associated with a significant decrease in breast ...
Three retrospective studies have recently reported an association between beta-blocker use and a reduction in breast cancer metastasis and recurrence. No prospective, randomized trials have been published.
Med Lett Drugs Ther. 2012 Jan 23;54(1382):6-7 |  Show IntroductionHide Introduction

In Brief: Lisocabtagene Maraleucel (Breyanzi) for Large B-Cell Lymphoma (online only)

   
The Medical Letter on Drugs and Therapeutics • Jun 26, 2023  (Issue 1679)
, followed by high-dose chemotherapy and, in responders, autologous stem cell transplantation). Event-free ...
The FDA has approved lisocabtagene maraleucel (Breyanzi – BMS) for treatment of adults with large B-cell lymphoma (LBCL), including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, high-grade B-cell lymphoma, primary mediastinal large B-cell lymphoma, or follicular lymphoma grade 3B who have disease refractory to first-line chemoimmunotherapy, relapsed within 12 months of or after first-line chemoimmunotherapy, are not eligible for hematopoietic stem cell transplantation due to comorbidities or age, or have relapsed or refractory disease after ≥2 lines of...
Med Lett Drugs Ther. 2023 Jun 26;65(1679):e104-5   doi:10.58347/tml.2023.1679f |  Show IntroductionHide Introduction

Azacitidine (Vidaza) for Myelodysplastic Syndrome

   
The Medical Letter on Drugs and Therapeutics • Jan 31, 2005  (Issue 1201)
chemotherapy regimens, such as cytarabine (Cytosar-U, and others) plus the anthracycline doxorubicin ...
Azacitidine (Vidaza - Pharmion), a pyrimidine nucleoside analog of cytidine, is the first drug approved by the FDA for treatment of myelodysplastic syndrome (MDS). Azacitidine is incorporated into newly synthesized DNA and inhibits DNA methyltransferase. Hypomethylation of DNA can restore the normal expression of genes critical for cell differentiation.
Med Lett Drugs Ther. 2005 Jan 31;47(1201):11 |  Show IntroductionHide Introduction

Panitumumab (Vectibix) for Metastatic Colorectal Cancer

   
The Medical Letter on Drugs and Therapeutics • Apr 23, 2007  (Issue 1259)
that has progressed despite standard chemotherapy. It is the second monoclonal antibody EGFR inhibitor to be approved ...
Panitumumab (Vectibix - Amgen), a fully human IgG2 monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), has been approved by the FDA for treatment of patients with EGFR-expressing metastatic colorectal cancer that has progressed despite standard chemotherapy. It is the second monoclonal antibody EGFR inhibitor to be approved for metastatic colorectal cancer; cetuximab (Erbitux), a human-murine chimeric IgG1 monoclonal antibody, was approved in 2004.
Med Lett Drugs Ther. 2007 Apr 23;49(1259):35-6 |  Show IntroductionHide Introduction

Epirubicin for Adjuvant Therapy in Node-Positive Breast Cancer

   
The Medical Letter on Drugs and Therapeutics • Feb 07, 2000  (Issue 1071)
or other hepatic impairment. CLINICAL TRIALS — Adjuvant chemotherapy regimens commonly used to treat breast ...
Epirubicin, an analog of doxorubicin that has been available in Europe and Canada for 15 years, has now been approved by the FDA for adjuvant use after resection of the primary tumor in breast cancer patients with axillary node involvement.
Med Lett Drugs Ther. 2000 Feb 7;42(1071):12-3 |  Show IntroductionHide Introduction

Adagrasib (Krazati) for NSCLC (online only)

   
The Medical Letter on Drugs and Therapeutics • Jan 23, 2023  (Issue 1668)
mutations whose disease had progressed on or after platinum-based chemotherapy and an immune checkpoint ...
Adagrasib (Krazati – Mirati Therapeutics), a RAS GTPase family inhibitor, has received accelerated approval from the FDA for oral treatment of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC) in adults who received at least one prior systemic therapy. Accelerated approval was based on the objective response rate and duration of response.
Med Lett Drugs Ther. 2023 Jan 23;65(1668):e17-8   doi:10.58347/tml.2023.1668f |  Show IntroductionHide Introduction