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Searched for activate. Results 391 to 400 of 1332 total matches.
Problems With Dietary Supplements
The Medical Letter on Drugs and Therapeutics • Sep 30, 2002 (Issue 1140)
and mid-1999 found that
the concentrations of listed ingredients thought to be active varied from lot ...
Millions of people now take herbal products and other "dietary supplements." The Physicians' Desk Reference has published a PDR for Herbal Medicines listing their ingredients and indications, and the Drug Topics Red Book lists their prices.
Adefovir (Hepsera) for Chronic Hepatitis B Infection
The Medical Letter on Drugs and Therapeutics • Dec 09, 2002 (Issue 1145)
of chronic active infection with hepatitis B virus (HBV). In 1999, because of concerns about renal toxicity ...
Adefovir dipivoxil (Hepsera - Gilead), a nucleotide analog, has been approved by the FDA for oral treatment of chronic active infection with hepatitis B virus (HBV). In 1999, because of concerns about renal toxicity, the FDA rejected a higher-dosage formulation of adefovir for treatment of HIV infection.
Augmentin XR
The Medical Letter on Drugs and Therapeutics • Jan 20, 2003 (Issue 1148)
, a cephalosporin such as cefuroxime axetil, or a quinolone with good antipneumococcal activity such as gatifloxacin ...
Augmentin XR (GlaxoSmithKline), an oral extended-release combination of amoxicillin and the beta-lactamase inhibitor clavulanic acid, is now being promoted for treatment of acute bacterial sinusitis and community-acquired pneumonia. Augmentin XR contains a higher dose of amoxicillin than Augmentin.
Resveratrol
The Medical Letter on Drugs and Therapeutics • Sep 21, 2009 (Issue 1321)
.
MECHANISM OF ACTION — Resveratrol increases
the activity of some sirtuin enzymes thought to be
involved ...
Resveratrol is a phytochemical found in the skin of red grapes and in many other plants, including berries, plums and peanuts. As a constituent of red wine, it has been associated with cardioprotective effects. Dietary supplements containing resveratrol are now being widely promoted as antioxidants that can prevent agerelated diseases.
Prasterone (Intrarosa) for Dyspareunia
The Medical Letter on Drugs and Therapeutics • Sep 11, 2017 (Issue 1529)
, and brain
and converted intracellularly into active metabolites
of estrogens and androgens. DHEA ...
The FDA has approved the steroid prasterone
(Intrarosa – Endoceutics) for intravaginal treatment
of postmenopausal women with moderate-to-severe
dyspareunia due to vulvovaginal atrophy (VVA). Also
called dehydroepiandrosterone (DHEA), prasterone
is produced in the adrenal glands, gonads, and brain
and converted intracellularly into active metabolites
of estrogens and androgens. DHEA has been available
over the counter for years as an oral dietary supplement
claimed to benefit sexual, cardiovascular, and
neuropsychiatric dysfunction.
Vibegron (Gemtesa) for Overactive Bladder
The Medical Letter on Drugs and Therapeutics • May 03, 2021 (Issue 1623)
whole or crushed and mixed with applesauce.
MECHANISM OF ACTION — Like mirabegron,
vibegron activates ...
The FDA has approved the selective beta-3 adrenergic
agonist vibegron (Gemtesa – Urovant Sciences)
for treatment of overactive bladder in adults with
symptoms of urge urinary incontinence, urgency, and
urinary frequency. It is the second beta-3 agonist to
be approved in the US; mirabegron (Myrbetriq) was
the first.
Berotralstat (Orladeyo) for Prevention of Hereditary Angioedema (online only)
The Medical Letter on Drugs and Therapeutics • Jul 26, 2021 (Issue 1629)
activation and
production of bradykinin by covalently binding to and
inactivating plasma kallikrein ...
Berotralstat (Orladeyo – Biocryst), an oral plasma
kallikrein inhibitor, has been approved by the FDA
for prevention of hereditary angioedema (HAE)
attacks in adults and children ≥12 years old. The
subcutaneously-injected plasma kallikrein inhibitor
lanadelumab-flyo (Takhzyro) and the human plasma-derived
C1 esterase inhibitors (C1INHs) Cinryze, which
is given IV, and Haegarda, which is given SC, have been
available for prophylaxis of HAE for years.
DaxibotulinumtoxinA (Daxxify) for Frown Lines (online only)
The Medical Letter on Drugs and Therapeutics • Jul 22, 2024 (Issue 1707)
with corrugator and/or procerus muscle activity. Daxxify is the fifth botulinumtoxin type A product to be approved ...
The FDA has approved daxibotulinumtoxinA-lanm
(Daxxify – Revance), an acetylcholine release inhibitor
and neuromuscular blocking agent, for temporary
improvement in the appearance of moderate to severe
glabellar (frown) lines associated with corrugator
and/or procerus muscle activity. Daxxify is the fifth
botulinumtoxin type A product to be approved in the
US for this indication (see Table 1). It is also approved
for treatment of cervical dystonia in adults
Med Lett Drugs Ther. 2024 Jul 22;66(1707):e121-2 doi:10.58347/tml.2024.1707g | Show Introduction Hide Introduction
Drug Interactions
The Medical Letter on Drugs and Therapeutics • Jun 08, 2003 (Issue 1158)
, but usually not to a clinically important
degree. Drugs that inhibit the activity of CYP isozymes without ...
Changes caused by one drug in the absorption, distribution, metabolism or excretion of another may lead to a pharmacokinetic adverse drug interaction (DN Juurlink et al, JAMA 2003; 289:1652). Additive drug interactions, such as vasodilation caused by both sildenafil (Viagra) and nitrates, can also have adverse effects.
Atazanavir (Reyataz) and Emtricitabine (Emtriva) for HIV Infection
The Medical Letter on Drugs and Therapeutics • Nov 10, 2003 (Issue 1169)
. Emtricitabine is a fluorinated derivative of lamivudine. Like lamivudine, it is also active
against hepatitis B ...
Atazanavir (Reyataz - Bristol-Myers Squibb), a new protease inhibitor (PI), and emtricitabine (Emtriva - Gilead), a nucleoside analogue reverse transcriptase inhibitor (NRTI) chemically similar to lamivudine, have been approved by the FDA for treatment of HIV-1 infection. Both are taken once daily, unlike most anti-HIV drugs.