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Searched for action. Results 521 to 530 of 1159 total matches.
Diazoxide Choline (Vykat XR) for Prader-Willi Syndrome-Associated Hyperphagia (online only)
The Medical Letter on Drugs and Therapeutics • Apr 28, 2025 (Issue 1727)
, which can lead to severe
obesity.1
MECHANISM OF ACTION — Diazoxide choline, a
nondiuretic ...
The FDA has approved diazoxide choline extended-release
tablets (Vykat XR – Soleno Therapeutics) for
treatment of hyperphagia in patients ≥4 years old
with Prader-Willi syndrome. Diazoxide choline is the
first drug to be approved in the US for this indication.
Diazoxide oral suspension (Proglycem) has been
available for years for management of symptomatic
hypoglycemia.
Med Lett Drugs Ther. 2025 Apr 28;67(1727):e72-3 doi:10.58347/tml.2025.1727e | Show Introduction Hide Introduction
Drugs for Stable Angina Pectoris
The Medical Letter on Drugs and Therapeutics • Dec 09, 1994 (Issue 937)
in onset of action than
sublingual nitroglycerin and less effective for treatment of acute angina. Its one ...
Many nitrates, beta-blockers, and calcium-channel blockers have now been approved by the US Food and Drug Administration for treatment of stable angina pectoris. The table beginning on page 112 lists the individual drugs, their dosage, and their cost.
Exenatide (Byetta) for Type 2 Diabetes
The Medical Letter on Drugs and Therapeutics • Jun 06, 2005 (Issue 1210)
, and others), or both.
Exenatide is not indicated for use with insulin.
MECHANISM OF ACTION — Several ...
Exenatide injection (Byetta - Amylin/Lilly), a synthetic peptide that stimulates release of insulin from pancreatic beta cells, has been approved by the FDA as adjunctive therapy for patients with type 2 diabetes who have not achieved optimal glycemic control on metformin (Glucophage, and others), a sulfonylurea, such as glyburide (DiaBeta, and others), or both. Exenatide is not indicated for use with insulin.
Azelastine (Astepro) Nasal Spray for Allergic Rhinitis
The Medical Letter on Drugs and Therapeutics • Apr 20, 2009 (Issue 1310)
of allergic rhinitis; they have a more
rapid onset of action, but they may cause sedation.
Intranasal ...
A new formulation of the H1-antihistamine azelastine hydrochloride 0.1% nasal spray (Astepro - Meda) has been approved by the FDA for treatment of seasonal allergic rhinitis (SAR) in patients ≥12 years old and is being heavily advertised to the public on radio, television and the Internet. All azelastine products require a prescription.
Lacosamide for Epilepsy
The Medical Letter on Drugs and Therapeutics • Jun 29, 2009 (Issue 1315)
. Pharmacology
MECHANISM OF ACTION — Lacosamide is a functional amino acid, structurally related to serine. Its ...
The FDA has approved lacosamide (Vimpat - UCB Pharma) for oral or intravenous (IV) use as add-on therapy in adults with partial-onset seizures.
IV Amisulpride (Barhemsys) for Postoperative Nausea and Vomiting
The Medical Letter on Drugs and Therapeutics • Dec 28, 2020 (Issue 1614)
at high risk for PONV, prophylaxis with ≥2
antiemetics with different mechanisms of action is
preferred ...
The FDA has approved IV amisulpride (Barhemsys –
Acacia), a selective dopamine-2 and -3 (D2/D3) receptor
antagonist, for prevention and treatment of postoperative
nausea and vomiting (PONV) in adults. It is the first
antiemetic to be approved for rescue treatment of
PONV in patients who have symptoms despite receiving
antiemetic prophylaxis. Oral formulations of amisulpride
are available in Europe for treatment of schizophrenia
and acute psychotic episodes.
New Copper IUD
The Medical Letter on Drugs and Therapeutics • Feb 26, 1988 (Issue 760)
), is the
other.
MECHANISM OF ACTION — IUDs stimulate a mild inflammatory reaction in the uterus,
increasing the number ...
The copper T 380A (ParaGard - GynoPharma), a new intrauterine contraceptive device (IUD) soon to be marketed in the USA, will be one of only two IUDs available in this country. Progestasert (Alza), which gradually releases progesterone (Medical Letter, 18:65, 1976), is the other.
Nimodipine for Cerebral Vasospasm Subarachnoid Hemorrhage
The Medical Letter on Drugs and Therapeutics • May 19, 1989 (Issue 792)
is available only for investigational use.
MECHANISM OF ACTION — Nimodipine is structurally related ...
Cerebral arterial spasm frequently causes ischemic neurological damage after subarachnoid hemorrhage from a ruptured intracranial aneurysm. Nimodipine (Nimotop - Miles), a 1,4-dihydropyridine calcium-entry blocker, was recently approved by the US Food and Drug Administration (FDA) for oral treatment of such patients; an intravenous preparation is available only for investigational use.
Nafarelin For Endometriosis
The Medical Letter on Drugs and Therapeutics • Aug 24, 1990 (Issue 825)
available products with this mechanism of action include, in addition to nafarelin, leuprolide (Lupron ...
Nafarelin acetate (Synarel - Syntex), a synthetic analog of gonadotropin-releasing hormone (GnRH), was recently approved by the US Food and Drug Administration for treatment of endometriosis. The drug is available only in a nasal spray formulation.
Ondansentron To Prevent Vomiting After Cancer Chemotherapy
The Medical Letter on Drugs and Therapeutics • Jun 28, 1991 (Issue 847)
with lorazepam (Ativan, and others).
PHARMACOLOGY — Ondansetron antagonizes the depolarizing action of serotonin ...
Ondansetron (on dan' se tron; Zofran - Glaxo), a serotonin (5-hydroxytryptamine) antagonist, was recently marketed in the USA for intravenous use to prevent nausea and vomiting due to cancer chemotherapy. An oral formulation is available in many other countries.