The Medical Letter on Drugs and Therapeutics
In Brief: Esomeprazole Strontium
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Med Lett Drugs Ther. 2014 Jul 21;56(1447):64
 Select a term to see related articles  Aciphex   Dexilant   Dexlansoprazole   esomeprazole strontium   GERD   lansoprazole   Losec   Nexium   omeprazole   Pantoloc   Pantoprazole   Prevacid   Prilosec   Proton pump inhibitors   Protonix   Rabeprazole 

The FDA has approved the proton pump inhibitor (PPI) esomeprazole strontium for use in adults for the same indications as esomeprazole magnesium (Nexium): treatment of gastroesophageal reflux disease (GERD), prevention of NSAID-induced gastric ulcers, eradication of Helicobacter pylori, and treatment of pathological hypersecretory conditions. It was first marketed in December 2013 as a branded drug (Esomeprazole Strontium) and a month later as a generic drug.

Strontium is incorporated into bone. It is not recommended for use in children or during pregnancy because of the absence of safety data in those populations. Use of esomeprazole strontium is not recommended for patients with severe renal impairment.

Esomeprazole strontium is the seventh PPI to become available as a single agent in the US. No new clinical trials were required for its approval, which was based on earlier clinical trials with esomeprazole magnesium. All of the PPIs appear to be equally effective.1

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