The Medical Letter on Drugs and Therapeutics
Issue 1522
Drugs for Opioid Use Disorder; Abuse-Deterrent Opioids; Comparison Table: Some Drugs for Maintenance Treatment of Opioid Use Disorder (online only)
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Drugs for Opioid Use Disorder
Opioid use disorder is a chronic, relapsing disease with both physical and psychiatric components. It is associated with economic hardship, social isolation, incarceration, increased rates of blood-borne infections such as HIV and viral hepatitis, adverse pregnancy outcomes, and increased mortality. According to the CDC, there were 33,091 deaths related to opioid overdose in the US in 2015, more than in any previous year. Several guidelines on the management of opioid use disorder have recently been published. ... more
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