Search Results for "Drug Interactions"
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Searched for Drug Interactions. Results 721 to 730 of 1090 total matches.
Glucagon Nasal Powder (Baqsimi) for Severe Hypoglycemia
The Medical Letter on Drugs and Therapeutics • Sep 23, 2019 (Issue 1581)
catecholamine release from the tumor) or
an insulinoma.
DRUG INTERACTIONS – Patients taking the NSAID ...
The FDA has approved glucagon nasal powder
(Baqsimi – Lilly) for treatment of severe hypoglycemia
in patients ≥4 years old with diabetes. Baqsimi is the
first noninjectable glucagon formulation to become
available in the US. Injectable glucagon emergency kits
(GlucaGen Hypokit, and generic) have been available
for years, but they require reconstitution of the
lyophilized powder by the caregiver immediately before
injection. An injectable glucagon formulation that does
not require reconstitution was recently approved by the
FDA (Gvoke) and is expected to become available...
Symfi, Symfi Lo, and Cimduo for HIV (online only)
The Medical Letter on Drugs and Therapeutics • Jan 14, 2019 (Issue 1563)
DRUG INTERACTIONS — Efavirenz is an inducer of
CYP3A, CYP2B6, and CYP2C1912; it can reduce serum ...
The FDA has approved three new once-daily fixed-dose
antiretroviral drug combinations for treatment of HIV-1 infection. Symfi and Symfi Lo (Mylan) contain the
non-nucleoside reverse transcriptase inhibitor (NNRTI)
efavirenz and the nucleoside reverse transcriptase
inhibitors (NRTIs) lamivudine and tenofovir disoproxil
fumarate (TDF) and were approved as complete
antiretroviral regimens. Symfi Lo contains a lower
dose of efavirenz than both Symfi and Atripla, a fixed-dose
combination of efavirenz, TDF, and the NRTI
emtricitabine that was approved in 2006. Cimduo
(Mylan), which...
Stiripentol (Diacomit) for Dravet Syndrome (online only)
The Medical Letter on Drugs and Therapeutics • Mar 24, 2021 (Issue 1620)
, and may interact with many other drugs.
▶ The cost of 30 days’ treatment for a child weighing 20 kg is $3000 ...
The FDA has approved stiripentol (Diacomit – Biocodex)
for treatment of seizures in patients ≥2 years old with
Dravet syndrome who are also taking clobazam (Onfi).
Stiripentol, which has been available in Europe, Canada,
and Japan for many years, is the second drug to be
approved in the US for this indication; cannabidiol oral
solution (Epidiolex), a purified marijuana product, was
the first.
Rufinamide (Banzel) for Epilepsy
The Medical Letter on Drugs and Therapeutics • Mar 09, 2009 (Issue 1307)
in the offspring of animals treated with rufinamide during pregnancy.
DRUG INTERACTIONS — Serum concentrations ...
Rufinamide (Banzel - Eisai), a triazole derivative structurally unrelated to other marketed antiepileptic drugs (AEDs), has been approved by the FDA for treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients ≥4 years old.
Duloxetine (Cymbalta): A New SNRI for Depression
The Medical Letter on Drugs and Therapeutics • Oct 11, 2004 (Issue 1193)
; it should probably not be used during
pregnancy or breast feeding.
DRUG INTERACTIONS — Duloxetine ...
Duloxetine hydrochloride (Cymbalta - Lilly), a selective serotonin and norepinephrine reuptake inhibitor (SNRI), has been approved by the FDA for treatment of major depressive disorder in adults, and more recently for diabetic peripheral neuropathy as well. The Medical Letter will review its role in diabetic neuropathy in a future issue.
Atazanavir (Reyataz) and Emtricitabine (Emtriva) for HIV Infection
The Medical Letter on Drugs and Therapeutics • Nov 10, 2003 (Issue 1169)
emtricitabine is withdrawn.
DRUG INTERACTIONS — Atazanavir inhibits the activity of CYP3A4 and may increase ...
Atazanavir (Reyataz - Bristol-Myers Squibb), a new protease inhibitor (PI), and emtricitabine (Emtriva - Gilead), a nucleoside analogue reverse transcriptase inhibitor (NRTI) chemically similar to lamivudine, have been approved by the FDA for treatment of HIV-1 infection. Both are taken once daily, unlike most anti-HIV drugs.
Pomalidomide (Pomalyst) for Multiple Myeloma (online only)
The Medical Letter on Drugs and Therapeutics • Apr 27, 2015 (Issue 1467)
stopping the drug.
DRUG INTERACTIONS — Pomalidomide is primarily
metabolized by CYP3A4 and CYP1A2 ...
The FDA has approved pomalidomide (Pomalyst –
Celgene), an oral thalidomide analog, for treatment
of patients with multiple myeloma who have received
at least 2 prior therapies including lenalidomide
(Revlimid) and bortezomib (Velcade) and whose
disease had progressed on or within 60 days of
completion of the last therapy.
Givinostat (Duvyzat) for Duchenne Muscular Dystrophy
The Medical Letter on Drugs and Therapeutics • Jun 07, 2024 (Issue 5074)
.
DRUG INTERACTIONS — Givinostat is a weak inhibitor
of CYP3A4 and the renal uptake transporter OCT2 ...
Givinostat (Duvyzat – Italfarmaco), an oral histone
deacetylase inhibitor, has been approved by the FDA
for treatment of patients ≥6 years old with Duchenne
muscular dystrophy (DMD), regardless of the DMD-causing
mutation. It is the first nonsteroidal drug to be
approved for this indication. The oral corticosteroids
deflazacort (Emflaza) and vamorolone (Agamree)
are also approved for treatment of patients with all
genetic variants of DMD.
Med Lett Drugs Ther. 2024 Jun 7;66(5074):1-2 doi:10.58347/tml.2024.5074a | Show Introduction Hide Introduction
Bioidentical Hormones
The Medical Letter on Drugs and Therapeutics • May 31, 2010 (Issue 1339)
with bioidentical hormone therapy
has been reported.
5
DRUG INTERACTIONS — Bioidentical estrogen preparations ...
In recent years, many women have become concerned about the safety of pharmaceutical replacement
hormones for treatment of menopausal symptoms. “Bioidentical” hormone preparations, which are not approved by the FDA, are heavily promoted in popular books and on TV as alternatives; these are
derivatives of soy or plant extracts, chemically modified to be structurally identical to endogenous hormones.
Most FDA-approved single-entity hormones are also derivatives of soy or plant extracts and are
structurally identical to hormones produced by the ovary.
Vardenafil (Levitra) for Erectile Dysfunction
The Medical Letter on Drugs and Therapeutics • Sep 29, 2003 (Issue 1166)
) or sotalol (Betapace, and others).
DRUG INTERACTIONS — If vardenafil is taken concurrently with potent 3A4 ...
Vardenafil (Levitra -Bayer) is the second oral drug approved by the FDA for treatment of erectile dysfunction. Sildenafil (Viagra - Medical Letter 1998; 40:51), the first oral drug, has been available for 5 years. Pharmacokinetics, effectiveness, adverse effects, dosage and cost of the new drug are reviewed. Whether it offers any benefits over sildenafil is discussed.