Search Results for "Linzess"
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Searched for Linzess. Results 1 to 10 of 12 total matches.
See also: linaclotide

Linaclotide (Linzess) for Constipation

   
The Medical Letter on Drugs and Therapeutics • Nov 12, 2012  (Issue 1403)
Linaclotide (Linzess) for Constipation ...
Linaclotide (lin´´ a kloe´ tide; Linzess – Ironwood/Forest), a guanylate cyclase-C receptor agonist, was recently approved by the FDA for oral treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) in adults. It is the second drug approved for this indication; lubiprostone (Amitiza), a metabolite of prostaglandin E1, was the first.
Med Lett Drugs Ther. 2012 Nov 12;54(1403):91-2 |  Show IntroductionHide Introduction

Linaclotide (Linzess) for Functional Constipation

   
The Medical Letter on Drugs and Therapeutics • Aug 21, 2023  (Issue 1683)
Linaclotide (Linzess) for Functional Constipation ...
The guanylate cyclase-C receptor agonist linaclotide (Linzess – Abbvie/Ironwood) was first approved by the FDA in 2012 for treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation in adults. The drug has now been approved for treatment of functional constipation in patients 6-17 years old. Linaclotide is the only drug to be approved in the US for treatment of functional constipation.
Med Lett Drugs Ther. 2023 Aug 21;65(1683):135-6   doi:10.58347/tml.2023.1683d |  Show IntroductionHide Introduction

Comparison Chart: Some Drugs for Irritable Bowel Syndrome with Constipation (IBS-C) (online only)

   
The Medical Letter on Drugs and Therapeutics • Feb 03, 2025  (Issue 1721)
of lubiprostone Guanylate Cyclase-C Agonists Linaclotide – Linzess (Abbvie/Ironwood) 72, 145, 290 mcg caps ...
View the Comparison Chart: Some Drugs for Irritable Bowel Syndrome with Constipation (IBS-C)
Med Lett Drugs Ther. 2025 Feb 3;67(1721):e1-3   doi:10.58347/tml.2025.1721e |  Show IntroductionHide Introduction

Plecanatide (Trulance) for Chronic Idiopathic Constipation

   
The Medical Letter on Drugs and Therapeutics • Apr 24, 2017  (Issue 1519)
constipation (CIC) in adults. Linaclotide (Linzess), another guanylate cyclase-C receptor agonist ...
The FDA has approved plecanatide (Trulance – Synergy), a guanylate cyclase-C receptor agonist, for treatment of chronic idiopathic constipation (CIC) in adults. Linaclotide (Linzess), another guanylate cyclase-C receptor agonist, and lubiprostone (Amitiza), a chloride channel activator, were approved earlier for treatment of CIC in adults.
Med Lett Drugs Ther. 2017 Apr 24;59(1519):66-8 |  Show IntroductionHide Introduction

Figure 1: Treatments for Irritable Bowel Syndrome (IBS) in Adults (online only)

   
The Medical Letter on Drugs and Therapeutics • Feb 03, 2025  (Issue 1721)
cholestyramine colesevelam colestipol rifaximin ondansetron Zofran eluxadoline Viberzi alosetron Linzess ...
View Figure: Treatments for Irritable Bowel Syndrome (IBS) in Adults
Med Lett Drugs Ther. 2025 Feb 3;67(1721):e1   doi:10.58347/tml.2025.1721c |  Show IntroductionHide Introduction

Comparison Chart: Safety of Drugs for IBS in Pregnancy and Lactation (online only)

   
The Medical Letter on Drugs and Therapeutics • Feb 03, 2025  (Issue 1721)
or its effects on milk production Linaclotide (Linzess) ▶ No adequate studies in pregnant women ...
View the Comparison Chart: Safety of Drugs for IBS in Pregnancy and Lactation
Med Lett Drugs Ther. 2025 Feb 3;67(1721):e1-2   doi:10.58347/tml.2025.1721b |  Show IntroductionHide Introduction

Vibrant – An Oral Vibrating Capsule for Chronic Idiopathic Constipation

   
The Medical Letter on Drugs and Therapeutics • May 01, 2023  (Issue 1675)
with these remedies.2 Prescription options, which include the prosecretory drugs linaclotide (Linzess), plecanatide ...
The Vibrant orally administered vibrating capsule (Vibrant Gastro), an FDA-cleared medical device, is now available by prescription for treatment of adults with chronic idiopathic constipation (CIC) who have not experienced relief of their bowel symptoms by using laxative therapies at the recommended dosage for at least one month. It is the first drug-free treatment to be authorized by the FDA for this indication.
Med Lett Drugs Ther. 2023 May 1;65(1675):65-7   doi:10.58347/tml.2023.1675a |  Show IntroductionHide Introduction

Prucalopride (Motegrity) for Chronic Idiopathic Constipation

   
The Medical Letter on Drugs and Therapeutics • Jun 03, 2019  (Issue 1573)
drug such as linaclotide (Linzess), plecanatide (Trulance), or lubiprostone (Amitiza ...
The FDA has approved the 5-HT4 receptor agonist prucalopride (Motegrity – Shire) for treatment of chronic idiopathic constipation (CIC) in adults. Prucalopride is the only drug currently approved in the US for treatment of CIC that stimulates colonic peristalsis. It has been available in Europe and Canada for several years.
Med Lett Drugs Ther. 2019 Jun 3;61(1573):86-8 |  Show IntroductionHide Introduction

Tenapanor (Ibsrela) for Irritable Bowel Syndrome with Constipation

   
The Medical Letter on Drugs and Therapeutics • Jun 13, 2022  (Issue 1652)
, a secretagogue such as lubiprostone (Amitiza, and generics), linaclotide (Linzess), or plecanatide (Trulance ...
The FDA has approved tenapanor (Ibsrela - Ardelyx), a sodium/hydrogen exchanger 3 (NHE3) inhibitor, for twice-daily oral treatment of irritable bowel syndrome with constipation (IBS-C) in adults. Tenapanor is the first NHE3 inhibitor to become available in the US.
Med Lett Drugs Ther. 2022 Jun 13;64(1652):91-4 |  Show IntroductionHide Introduction

Expanded Table: Some Drugs for Chronic Idiopathic Constipation (online only)

   
The Medical Letter on Drugs and Therapeutics • Jun 03, 2019  (Issue 1573)
Linaclotide2 – Linzess (Allergan/Ironwood) 72, 145, 290 mcg caps 145 mcg PO once/day ≥30 mins before ...
View the Expanded Table: Some Drugs for Chronic Idiopathic Constipation
Med Lett Drugs Ther. 2019 Jun 3;61(1573):e88-90 |  Show IntroductionHide Introduction