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Searched for days. Results 31 to 40 of 484 total matches.

Twirla - A New Contraceptive Patch

   
The Medical Letter on Drugs and Therapeutics • Feb 08, 2021  (Issue 1617)
-label trial (SECURE) that included 1736 women 18-35 years old who completed 15,165 evaluable 28-day ...
The FDA has approved Twirla (Agile Therapeutics), a transdermal contraceptive patch containing the estrogen ethinyl estradiol and the progestin levonorgestrel, for use in women with a BMI <30 kg/m2. It is the second contraceptive patch to become available in the US; Xulane, a patch that delivers ethinyl estradiol and the progestin norelgestromin, has been available since 2014.
Med Lett Drugs Ther. 2021 Feb 8;63(1617):17-8 |  Show IntroductionHide Introduction

COVID-19 Updates

   
The Medical Letter on Drugs and Therapeutics • Feb 21, 2022  (Issue 1644)
days previously and had one or more risk factors for progression to severe COVID-19 (e.g., age ≥60 ...
The IV antiviral drug remdesivir (Veklury – Gilead) has been available for treatment of COVID-19 in hospitalized patients since 2020. Now, the FDA has approved remdesivir for treatment of mild to moderate COVID-19 in outpatients ≥12 years old who weigh ≥40 kg and are at high risk for progression to severe disease, including hospitalization or death; they also issued an Emergency Use Authorization (EUA) allowing its use in any other high-risk outpatient who weighs ≥3.5 kg.
Med Lett Drugs Ther. 2022 Feb 21;64(1644):31-2 |  Show IntroductionHide Introduction

Teplizumab (Tzield) to Delay Onset of Type 1 Diabetes

   
The Medical Letter on Drugs and Therapeutics • Jan 09, 2023  (Issue 1667)
peptides Half-life (elimination) 4.5 days Teplizumab-mzwv (Tzield – Provention Bio), an anti- CD3 ...
Teplizumab-mzwv (Tzield – Provention Bio), an anti-CD3 monoclonal antibody, has been approved by the FDA to delay the onset of stage 3 type 1 diabetes in patients ≥8 years old who have stage 2 type 1 diabetes. It is the first drug to become available in the US that delays the onset of type 1 diabetes.
Med Lett Drugs Ther. 2023 Jan 9;65(1667):7-8   doi:10.58347/tml.2023.1667c |  Show IntroductionHide Introduction

Ganaxolone (Ztalmy) for CDKL5 Deficiency Disorder (online only)

   
The Medical Letter on Drugs and Therapeutics • Aug 19, 2024  (Issue 1709)
/day titrated to 63 mg/kg/day; >28 kg: 450 mg/day titrated to 1800 mg/day. ▶ Cost: 30 days ...
The FDA has approved ganaxolone (Ztalmy – Marinus) for oral treatment of seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder in patients ≥2 years old. It is the first drug to be approved in the US for this indication.
Med Lett Drugs Ther. 2024 Aug 19;66(1709):e139-40   doi:10.58347/tml.2024.1709g |  Show IntroductionHide Introduction

Drugs for Hypertension

   
The Medical Letter on Drugs and Therapeutics • May 27, 2024  (Issue 1703)
such as the Dietary Approaches to Stop Hypertension (DASH) diet,2 limiting intake of sodium (ideally ...
American College of Cardiology/American Heart Association (ACC/AHA) guidelines for treatment of hypertension were last published in 2018. Treatment of hypertensive urgencies and emergencies is not discussed here.
Med Lett Drugs Ther. 2024 May 27;66(1703):81-8   doi:10.58347/tml.2024.1703a |  Show IntroductionHide Introduction

Comparison Chart: Some Drugs for Irritable Bowel Syndrome with Diarrhea (IBS-D) (online only)

   
The Medical Letter on Drugs and Therapeutics • Feb 03, 2025  (Issue 1721)
) 5.8 g/teaspoon powder; 5.8 g packets; 1.8 g caps; 2 g wafers $29.00 10-35 g/day in 2-3 divided ...
View the Comparison Chart: Some Drugs for Irritable Bowel Syndrome with Diarrhea (IBS-D)
Med Lett Drugs Ther. 2025 Feb 3;67(1721):e1-3   doi:10.58347/tml.2025.1721f |  Show IntroductionHide Introduction

Comparison Table: Some Drugs for Maintenance Treatment of Opioid Use Disorder (online only)

   
The Medical Letter on Drugs and Therapeutics • Sep 04, 2023  (Issue 1684)
buprenorphine levels with 32 mg once weekly or 128 mg once monthly ~60% higher than those with 24 mg/day ...
View Comparison Table: Some Drugs for Maintenance Treatment of Opioid Use Disorder
Med Lett Drugs Ther. 2023 Sep 4;65(1684):e144-5   doi:10.58347/tml.2023.1684b |  Show IntroductionHide Introduction

COVID-19 Update: Metformin to Prevent Long Covid?

   
The Medical Letter on Drugs and Therapeutics • May 29, 2023  (Issue 1677)
years old with an elevated body mass index who had tested positive for SARS-CoV-2 infection ≤3 days ...
Results from a double-blind trial suggest that off-label use of the oral antihyperglycemic drug metformin in patients with COVID-19 may decrease the risk of post-acute sequelae of SARS-CoV-2 infection ("long COVID").
Med Lett Drugs Ther. 2023 May 29;65(1677):87-8   doi:10.58347/tml.2023.1677e |  Show IntroductionHide Introduction

In Brief: Alternatives to Mifepristone for Medication Abortion

   
The Medical Letter on Drugs and Therapeutics • Jun 26, 2023  (Issue 1679)
(expulsion of the gestational sac without surgical intervention) of 97% in pregnancies of up to 70 days ...
The possibility that use of mifepristone (Mifeprex, and generics) may be restricted has led to questions about alternatives for medication abortion.
Med Lett Drugs Ther. 2023 Jun 26;65(1679):102-3   doi:10.58347/tml.2023.1679d |  Show IntroductionHide Introduction

Comparison Table: Some Drugs for Gout (online only)

   
The Medical Letter on Drugs and Therapeutics • Oct 30, 2023  (Issue 1688)
x 1 dose, then 200 mg PO 12 hrs later on day 1, followed by 200 mg PO bid $16.20 937.80 ...
View the Comparison Table: Some Drugs for Gout
Med Lett Drugs Ther. 2023 Oct 30;65(1688):e176-9   doi:10.58347/tml.2023.1688c |  Show IntroductionHide Introduction