The Medical Letter - 2006
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Year:    Publication:      2006 Annual Index: U.S. English | Canadian English
January 2, 2006 (Issue 1225)  
January 16, 2006 (Issue 1226)  
  • Adacel and Boostrix: Tdap Vaccines for Adolescents and Adults   
    The FDA has licensed Adacel (Aventis Pasteur) and Boostrix (GlaxoSmithKline), two new combination vaccines that include tetanus toxoid, diphtheria toxoid and acellular pertussis...
  • Drugs in the Elderly   
    The physiologic changes that occur with aging can affect the pharmacokinetics and pharmacodynamics of many prescription and over-the-counter drugs, increasing the likelihood of adverse effects.
  • Chromium Supplementation   
    Chromium is marketed as a dietary supplement, usually containing 20-500 mcg of a chromium salt. It has been promoted for weight loss, muscle building, and for prevention and treatment of diabetes,...
January 30, 2006 (Issue 1227)  
February 13, 2006 (Issue 1228)  
February 27, 2006 (Issue 1229)  
  • Abatacept (Orencia) for Rheumatoid Arthritis   
    Atacept (Orencia - Bristol-Myers Squibb), an inhibitor of T-cell activation, has been approved by the FDA for treatment of moderate to severe rheumatoid arthritis (RA) in patients who have...
  • Coenzyme Q10   
    Coenzyme Q10, a fat-soluble antioxidant also known as ubidecarenone, ubiquinone and CoQ10, is marketed as a dietary supplement in the US, both as a single ingredient and in various combination...
March 13, 2006 (Issue 1230)  
March 27, 2006 (Issue 1231)  
April 10, 2006 (Issue 1232)  
April 24, 2006 (Issue 1233)  
May 8, 2006 (Issue 1234)  
May 22, 2006 (Issue 1235)  
June 5, 2006 (Issue 1236)  
  • Mumps Outbreak Recommendations   
    A large mumps outbreak that began in Iowa in December 2005 has spread. About 40% of the cases have been in people 18-25 years old, many of whom are college students and had been vaccinated against...
  • Ranolazine (Ranexa) for Chronic Angina   
    The FDA has approved the marketing of extended release (ER) ranolazine (Ranexa - CV Therapeutics) for treatment of chronic angina in patients who have not achieved an adequate response with...
  • Lubiprostone (Amitiza) for Chronic Constipation   
    The FDA has approved lubiprostone (Amitiza - Sucampo/Takeda), a chloride channel activator, for treatment of chronic idiopathic constipation in adults. The only other prescription drug...
June 19, 2006 (Issue 1237)  
  • Transdermal Methylphenidates (Daytrana) for ADHD   
    A transdermal patch formulation of methylphenidate (Daytrana - Noven/Shire) has been approved by the FDA for treatment of attention-deficit/hyperactivity disorder (ADHD) in patients ≥ 6...
  • Conivaptan (Vaprisol) for Hyponatremia   
    Conivaptan hydrochloride (Vaprisol - Astellas), a vasopressin antagonist, has been approved by the FDA for short-term intravenous (IV) treatment of euvolemic hyponatremia in hospitalized...
  • In Brief: One Drop or Two   
    Many prescriptions for eye drops call for instillation of 1-2 drops. But Medical Letter consultants in ophthalmology seem to agree that all eye drops should generally be given in doses of only one...
July 3, 2006 (Issue 1238)  
July 17, 2006 (Issue 1239)  
  • Inhaled Insulin (Exubera)   
    An inhaled, dry-powder formulation of rapid-acting human insulin (Exubera - Pfizer) has been approved by the FDA for treatment of adults with type 1 or type 2 diabetes.
  • Fish Oil Supplements   
    Omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential human nutrients. The main dietary source of PUFAs is fatty fish...
July 31, 2006 (Issue 1240)  
August 14, 2006 (Issue 1241)  
September 11, 2006 (Issue 1243)  
  • Herpes Zoster Vaccine (Zostavax)   
    A live attenuated varicella-zoster vaccine (Zostavax - Merck) has been approved by the FDA for prevention of herpes zoster (HZ; zoster; shingles) in persons ≥60 years old. Each dose of...
  • Darunavir (Prezista) for HIV Infection   
    Darunavir (Prezista - Tibotec), a new protease inhibitor, has received accelerated approval from the FDA for use in combination therapy of human-immunodeficiency virus (HIV) infection in...
  • In Brief: Plan B OTC   
    The FDA has approved over-the-counter (OTC) sales of Plan B (Duramed), an emergency contraceptive package that contains two 0.75-mg tablets of levonorgestrel, to women ≥18 years old....
  • In Brief: Atorvastatin for Stroke Prevention   
    Statins have been shown to reduce the risk of stroke in patients at high risk for cardiovascular disease (Treat Guidel Med Lett 2005; 3:15). A recent issue of The New England Journal of Medicine...
  • In Brief: Natalizumab (Tysabri) Returns   
    Soon after The Medical Letter first reviewed use of natalizumab (Tysabri – Biogen Idec and Elan) for treatment of relapsing forms of multiple sclerosis (MS) (Med Lett Drugs Ther 2005;...
September 25, 2006 (Issue 1244)  
October 9, 2006 (Issue 1245)  
October 23, 2006 (Issue 1246)  
November 6, 2006 (Issue 1247)  
November 20, 2006 (Issue 1248)  
December 4, 2006 (Issue 1249)