The Medical Letter - 2016
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Year:    Publication:      2016 Annual Index: U.S. English | Canadian English
January 4, 2016 (Issue 1485)  
January 18, 2016 (Issue 1486)  
February 1, 2016 (Issue 1487)  
February 15, 2016 (Issue 1488)  
February 29, 2016 (Issue 1489)  
March 14, 2016 (Issue 1490)  
March 28, 2016 (Issue 1491)  
April 11, 2016 (Issue 1492)  
April 25, 2016 (Issue 1493)  
May 9, 2016 (Issue 1494)  
May 23, 2016 (Issue 1495)  
June 6, 2016 (Issue 1496)  
June 20, 2016 (Issue 1497)  
July 4, 2016 (Issue 1498)  
  • Insect Repellents   
    Use of insect repellents is strongly recommended by the CDC and the EPA to prevent Zika virus infection and other mosquito- and tickborne diseases. Mosquitoes can transmit chikungunya, dengue,...
  • Drugs for Depression   
    Complete remission of symptoms is the goal of antidepressant therapy; partial response is associated with an increased risk of relapse. Improvement can occur within the first two weeks of drug...
  • In Brief: Uridine Triacetate (Vistogard) for Fluorouracil Overdose   
    The FDA has approved the pyrimidine analog uridine triacetate (Vistogard – Wellstat Therapeutics) for emergency treatment of a fluorouracil (5-FU) or capecitabine (Xeloda, and...
July 18, 2016 (Issue 1499)  
August 1, 2016 (Issue 1500)  
August 15, 2016 (Issue 1501)  
  • Drugs for Bipolar Disorder   
    Bipolar disorder is characterized by intermittent episodes of mania and/or depression. Even with maintenance treatment, recurrences of manic or (more frequently) depressive episodes are common....
  • Sofosbuvir/Velpatasvir (Epclusa) for Hepatitis C   
    The FDA has approved Epclusa (Gilead), a fixed-dose combination of sofosbuvir (Sovaldi) and velpatasvir, a new direct-acting antiviral agent, for oral treatment of chronic hepatitis...
August 29, 2016 (Issue 1502)  
September 12, 2016 (Issue 1503)  
September 26, 2016 (Issue 1504)  
October 10, 2016 (Issue 1505)  
October 24, 2016 (Issue 1506)  
November 7, 2016 (Issue 1507)  
  • Metformin for Prediabetes   
    The oral biguanide metformin (Glucophage, and others) is generally the drug of choice for initial treatment of type 2 diabetes. It has also been used to prevent or at least delay the onset...
  • Drugs for Menopausal Symptoms   
    The primary symptoms of menopause are genitourinary and vasomotor. A thin, dry vaginal lining and thin urethral mucosa can cause vaginal and vulvar burning and irritation, pain during...
  • Eteplirsen (Exondys 51) for Duchenne Muscular Dystrophy   
    Eteplirsen (Exondys 51 – Sarepta), an antisense oligonucleotide, has received accelerated approval from the FDA for treatment of Duchenne muscular dystrophy (DMD) in patients who have a...
November 21, 2016 (Issue 1508)  
December 5, 2016 (Issue 1509)  
December 19, 2016 (Issue 1510)