Matching articles for "Amantadine"
Antiviral Drugs for Influenza for 2022-2023
The Medical Letter on Drugs and Therapeutics • November 28, 2022; (Issue 1664)
Influenza is generally a self-limited illness, but
complications such as pneumonia, respiratory
failure, and death can occur, especially in patients
at increased risk for influenza complications (see
Table...
Influenza is generally a self-limited illness, but
complications such as pneumonia, respiratory
failure, and death can occur, especially in patients
at increased risk for influenza complications (see
Table 1). Antiviral drugs recommended for treatment
and chemoprophylaxis of influenza this season are
listed in Table 2. Updated information on influenza
activity and antiviral resistance is available from the
CDC at www.cdc.gov/flu. None of the drugs that are
FDA-approved for treatment of influenza have clinically
relevant antiviral activity against SARS-CoV-2.
Antiviral Drugs for Influenza for 2021-2022
The Medical Letter on Drugs and Therapeutics • January 10, 2022; (Issue 1641)
Influenza is generally a self-limited illness, but
complications such as pneumonia, respiratory
failure, and death can occur, especially in patients
at higher risk for complications (see Table 1).
Antiviral...
Influenza is generally a self-limited illness, but
complications such as pneumonia, respiratory
failure, and death can occur, especially in patients
at higher risk for complications (see Table 1).
Antiviral drugs recommended for treatment and
chemoprophylaxis of influenza this season are listed
in Table 2. Updated information on influenza activity
and antiviral resistance is available from the CDC at
www.cdc.gov/flu.
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • February 22, 2021; (Issue 1618)
The motor symptoms of Parkinson's disease (PD) are
caused primarily by degeneration of dopaminergic
neurons in the substantia nigra. The nonmotor symptoms
of the disease are thought to be caused by...
The motor symptoms of Parkinson's disease (PD) are
caused primarily by degeneration of dopaminergic
neurons in the substantia nigra. The nonmotor symptoms
of the disease are thought to be caused by degeneration of
other neurotransmitter systems. No disease-modifying
drugs are available for treatment of PD.
Comparison Table: Drugs for Parkinson's Disease (online only)
The Medical Letter on Drugs and Therapeutics • February 22, 2021; (Issue 1618)
...
View the Comparison Table: Drugs for Parkinson's Disease
Antiviral Drugs for Influenza for 2020-2021
The Medical Letter on Drugs and Therapeutics • November 2, 2020; (Issue 1610)
Influenza is generally a self-limited illness, but
complications such as pneumonia, respiratory failure,
and death can occur, especially in patients at increased
risk for influenza complications (see Table...
Influenza is generally a self-limited illness, but
complications such as pneumonia, respiratory failure,
and death can occur, especially in patients at increased
risk for influenza complications (see Table 1).
Antiviral drugs recommended for treatment and
chemoprophylaxis of influenza this season are listed
in Table 2. Updated information on influenza activity
and antiviral resistance is available from the CDC at
www.cdc.gov/flu.
Istradefylline (Nourianz) for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • February 10, 2020; (Issue 1591)
The FDA has approved istradefylline (Nourianz —
Kyowa Kirin), an oral adenosine A2A receptor antagonist,
for use as an adjunct to carbidopa/levodopa in adults
with Parkinson's disease (PD) who experience...
The FDA has approved istradefylline (Nourianz —
Kyowa Kirin), an oral adenosine A2A receptor antagonist,
for use as an adjunct to carbidopa/levodopa in adults
with Parkinson's disease (PD) who experience "off"
episodes. Istradefylline is the first adenosine A2A
receptor antagonist to be approved in the US; it has
been available in Japan since 2013.
Osmolex ER - Another Extended-Release Amantadine for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • September 10, 2018; (Issue 1555)
The FDA has approved an extended-release tablet
formulation of amantadine (Osmolex ER – Vertical/Osmotica) for once-daily treatment of Parkinson's
disease (PD) and drug-induced extrapyramidal
symptoms...
The FDA has approved an extended-release tablet
formulation of amantadine (Osmolex ER – Vertical/Osmotica) for once-daily treatment of Parkinson's
disease (PD) and drug-induced extrapyramidal
symptoms (EPS) in adults. An extended-release
capsule formulation of amantadine (Gocovri) was
approved in 2017 for treatment of levodopa-induced
dyskinesia in patients with PD.
Antiviral Drugs for Seasonal Influenza 2017-2018
The Medical Letter on Drugs and Therapeutics • January 1, 2018; (Issue 1537)
Antiviral drugs can be used for treatment and prophylaxis
of influenza. Frequently updated information on
influenza activity, testing for influenza, and antiviral
resistance is available from the CDC at...
Antiviral drugs can be used for treatment and prophylaxis
of influenza. Frequently updated information on
influenza activity, testing for influenza, and antiviral
resistance is available from the CDC at www.cdc.gov/flu.
Extended-Release Amantadine (Gocovri) for Dyskinesia in Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • December 4, 2017; (Issue 1535)
The FDA has approved an extended-release (ER)
capsule formulation of amantadine (Gocovri –
Adamas) for once-daily treatment of levodopa-induced
dyskinesia in patients with Parkinson's
disease (PD). It is...
The FDA has approved an extended-release (ER)
capsule formulation of amantadine (Gocovri –
Adamas) for once-daily treatment of levodopa-induced
dyskinesia in patients with Parkinson's
disease (PD). It is the first product to be approved
in the US for this indication. Immediate-release (IR)
amantadine has been used off-label for years to
manage levodopa-induced dyskinesia.
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • November 20, 2017; (Issue 1534)
The motor symptoms of Parkinson's disease (PD) are
caused primarily by degeneration of dopaminergic
neurons in the substantia nigra. The nonmotor
symptoms of the disease are thought to be caused...
The motor symptoms of Parkinson's disease (PD) are
caused primarily by degeneration of dopaminergic
neurons in the substantia nigra. The nonmotor
symptoms of the disease are thought to be caused by
degeneration of other neurotransmitter systems.
Comparison Table: Drugs for Parkinson's Disease (online only)
The Medical Letter on Drugs and Therapeutics • November 20, 2017; (Issue 1534)
...
View the Comparison Table: Drugs for Parkinson's Disease
Safinamide (Xadago) for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • September 11, 2017; (Issue 1529)
The FDA has approved the monoamine oxidase
type B (MAO-B) inhibitor safinamide (Xadago – US
Worldmeds) as an adjunct to levodopa/carbidopa
for management of "off" episodes in patients with
Parkinson’s...
The FDA has approved the monoamine oxidase
type B (MAO-B) inhibitor safinamide (Xadago – US
Worldmeds) as an adjunct to levodopa/carbidopa
for management of "off" episodes in patients with
Parkinson’s disease (PD). It is the first reversible
MAO-B inhibitor to be approved for this indication.
Selegiline (Eldepryl, and others) and rasagiline
(Azilect, and generics), two irreversible MAO-B
inhibitors, have been used alone and as adjuncts to
levodopa/carbidopa for many years. Safinamide is
not approved for use as monotherapy.
Antiviral Drugs for Seasonal Influenza 2014-2015
The Medical Letter on Drugs and Therapeutics • December 8, 2014; (Issue 1457)
Antiviral drugs can be used for treatment of influenza
and as an adjunct to influenza vaccination for prophylaxis.
Frequently updated information on influenza
activity and antiviral resistance is available...
Antiviral drugs can be used for treatment of influenza
and as an adjunct to influenza vaccination for prophylaxis.
Frequently updated information on influenza
activity and antiviral resistance is available from the
CDC at www.cdc.gov/flu.
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • November 1, 2013; (Issue 135)
The motor symptoms of Parkinson's disease (PD) are
caused primarily by progressive degeneration of
dopaminergic neurons in the substantia nigra. The non-motor
symptoms of the disease are thought to be...
The motor symptoms of Parkinson's disease (PD) are
caused primarily by progressive degeneration of
dopaminergic neurons in the substantia nigra. The non-motor
symptoms of the disease are thought to be caused
by degeneration of other neurotransmitter systems.
Antiviral Drugs
The Medical Letter on Drugs and Therapeutics • March 1, 2013; (Issue 127)
The drugs of choice for treatment of viral infections
(other than HIV) and their dosages are listed in Tables
1-6 on the pages that follow. Some of the indications
and dosages recommended here have not...
The drugs of choice for treatment of viral infections
(other than HIV) and their dosages are listed in Tables
1-6 on the pages that follow. Some of the indications
and dosages recommended here have not been
approved by the FDA. Vaccines used for the prevention
of viral infections are discussed elsewhere.
Antiviral Drugs for Influenza 2012-2013
The Medical Letter on Drugs and Therapeutics • December 10, 2012; (Issue 1405)
Antiviral drugs can be used as an adjunct to
vaccination for prophylaxis and treatment of influenza.
In recent years, the susceptibility of circulating influenza
virus strains has evolved rapidly and...
Antiviral drugs can be used as an adjunct to
vaccination for prophylaxis and treatment of influenza.
In recent years, the susceptibility of circulating influenza
virus strains has evolved rapidly and treatment recommendations
have changed during the influenza season.
Frequently updated information on antiviral resistance is
available at www.cdc.gov/flu/professionals/antivirals.
Antiviral Drugs for Influenza
The Medical Letter on Drugs and Therapeutics • January 9, 2012; (Issue 1381)
Antiviral drugs can be used for treatment and prophylaxis
of influenza. In recent years, the susceptibility of
circulating influenza strains has evolved rapidly and
treatment recommendations have changed...
Antiviral drugs can be used for treatment and prophylaxis
of influenza. In recent years, the susceptibility of
circulating influenza strains has evolved rapidly and
treatment recommendations have changed during the
influenza season. The CDC influenza website provides
frequently updated information on antiviral resistance
(www.cdc.gov/flu).
Antiviral Drugs for Influenza
The Medical Letter on Drugs and Therapeutics • January 10, 2011; (Issue 1355)
Antiviral drugs can be used for treatment of patients with influenza and for prophylaxis when exposure to the disease occurs before or less than 2 weeks after vaccination. They can also be used to control...
Antiviral drugs can be used for treatment of patients with influenza and for prophylaxis when exposure to the disease occurs before or less than 2 weeks after vaccination. They can also be used to control institutional outbreaks of influenza. In recent years, the susceptibility of circulating influenza strains has evolved rapidly and treatment recommendations have changed during the influenza season. The CDC influenza web site provides frequently updated information on antiviral resistance (www.cdc.gov/flu)
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • January 1, 2011; (Issue 101)
Parkinson’s disease (PD) is caused primarily by progressive
degeneration of dopamine-containing neurons
in the substantia nigra. Dopamine itself cannot be
used to treat PD because it does not cross the...
Parkinson’s disease (PD) is caused primarily by progressive
degeneration of dopamine-containing neurons
in the substantia nigra. Dopamine itself cannot be
used to treat PD because it does not cross the blood-brain
barrier.
Drugs for Non-HIV Viral Infections
The Medical Letter on Drugs and Therapeutics • October 1, 2010; (Issue 98)
The drugs of choice for treatment of non-HIV viral
infections and their dosages are listed in Tables 1-6 on
the pages that follow. Some of the indications and
dosages recommended here have not been...
The drugs of choice for treatment of non-HIV viral
infections and their dosages are listed in Tables 1-6 on
the pages that follow. Some of the indications and
dosages recommended here have not been approved
by the FDA. Vaccines used for the prevention of viral
infections are discussed in another issue of Treatment
Guidelines.
Drugs Past Their Expiration Date
The Medical Letter on Drugs and Therapeutics • December 14, 2009; (Issue 1327)
Healthcare providers are often asked if patients can use drugs after their expiration date. Pharmaceutical companies, because of legal restrictions and liability concerns, will not sanction such use and might...
Healthcare providers are often asked if patients can use drugs after their expiration date. Pharmaceutical companies, because of legal restrictions and liability concerns, will not sanction such use and might not even comment on the safety or effectiveness of using their products beyond the date on the label. Since the last Medical Letter publication on this subject, more data have become available.
Antiviral Drugs for Influenza
The Medical Letter on Drugs and Therapeutics • November 16, 2009; (Issue 1325)
Currently circulating influenza virus is almost universally pandemic 2009 influenza A H1N1, but seasonal influenza strains could also appear soon. Antiviral drugs are an important adjunct to influenza...
Currently circulating influenza virus is almost universally pandemic 2009 influenza A H1N1, but seasonal influenza strains could also appear soon. Antiviral drugs are an important adjunct to influenza vaccination for treatment and chemoprophylaxis of both pandemic and seasonal influenza. They may, however, interfere with the efficacy of FluMist, the live-attenuated intranasal vaccine, if they are administered within 48 hours before or <2 weeks after FluMist administration. Inactivated vaccines are not affected by antiviral drug therapy.
More Resistance to Oseltamivir (Tamiflu)
The Medical Letter on Drugs and Therapeutics • January 26, 2009; (Issue 1304)
Since publication of our recent article on antiviral drugs for influenza, increased levels of resistance to oseltamivir (Tamiflu) have been detected in influenza A H1N1...
Since publication of our recent article on antiviral drugs for influenza, increased levels of resistance to oseltamivir (Tamiflu) have been detected in influenza A H1N1 strains.
Tetrabenazine (Xenazine) for Huntington's Chorea
The Medical Letter on Drugs and Therapeutics • January 26, 2009; (Issue 1304)
Tetrabenazine (Xenazine - Ovation Pharmaceuticals), an old drug first synthesized 50 years ago for treatment of schizophrenia, was recently approved by the FDA for the treatment of chorea associated with...
Tetrabenazine (Xenazine - Ovation Pharmaceuticals), an old drug first synthesized 50 years ago for treatment of schizophrenia, was recently approved by the FDA for the treatment of chorea associated with Huntington's disease. It has been available in other countries for decades.
Antiviral Drugs for Influenza
The Medical Letter on Drugs and Therapeutics • December 15, 2008; (Issue 1301)
Antiviral drugs are an important adjunct to influenza vaccination and can be used for treatment of patients with influenza within 2 days of the onset of illness and for chemoprophylaxis of influenza exposures...
Antiviral drugs are an important adjunct to influenza vaccination and can be used for treatment of patients with influenza within 2 days of the onset of illness and for chemoprophylaxis of influenza exposures that occur before or less than 2 weeks after vaccination. Patients who are immunocompromised or immunosuppressed, have pulmonary disease, are elderly or are healthcare workers may also be appropriate candidates for chemoprophylaxis.
Drugs That May Cause Psychiatric Symptoms
The Medical Letter on Drugs and Therapeutics • December 15, 2008; (Issue 1301)
Many drugs can cause psychiatric symptoms, but a causal connection is often difficult to establish. Psychiatric symptoms that emerge during drug treatment could also be due to the underlying illness, previously...
Many drugs can cause psychiatric symptoms, but a causal connection is often difficult to establish. Psychiatric symptoms that emerge during drug treatment could also be due to the underlying illness, previously unrecognized psychopathology, or psychosocial factors. The withdrawal of some drugs can cause symptoms such as anxiety, psychosis, delirium, agitation or depression.
Click here to view the free full article.
Click here to view the free full article.
Antiviral Drugs for Influenza
The Medical Letter on Drugs and Therapeutics • October 22, 2007; (Issue 1272)
Antiviral drugs can be used for treatment of patients with influenza and for prophylaxis of influenza exposures that occur before or less than 2 weeks after vaccination. They can also be used to control...
Antiviral drugs can be used for treatment of patients with influenza and for prophylaxis of influenza exposures that occur before or less than 2 weeks after vaccination. They can also be used to control institutional influenza outbreaks and for prophylaxis in years when circulating strains differ from those included in the vaccine.
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • October 1, 2007; (Issue 62)
ParkinsonÆs disease (PD) is caused primarily by progressive degeneration of dopamine-containing neurons in the substantia nigra. Dopamine itself cannot be used to treat PD because it does not cross the...
ParkinsonÆs disease (PD) is caused primarily by progressive degeneration of dopamine-containing neurons in the substantia nigra. Dopamine itself cannot be used to treat PD because it does not cross the bloodbrain barrier.
Drugs for Non-HIV Viral Infections
The Medical Letter on Drugs and Therapeutics • July 1, 2007; (Issue 59)
The drugs of choice for treatment of non-HIV viral infections with their dosages and cost are listed in Tables 1-6. Some of the indications and dosages recommended here have not been approved by the FDA....
The drugs of choice for treatment of non-HIV viral infections with their dosages and cost are listed in Tables 1-6. Some of the indications and dosages recommended here have not been approved by the FDA. Vaccines used in the prevention of viral infections are discussed in the "Adult Immunization" issue of Treatment Guidelines.
Antiviral Drugs for Prophylaxis and Treatment of Influenza
The Medical Letter on Drugs and Therapeutics • October 23, 2006; (Issue 1246)
Antiviral drugs can be used to control institutional influenza outbreaks and for prophylaxis of influenza exposures that occur before or less than 2 weeks after vaccination with inactivated vaccine, or in years...
Antiviral drugs can be used to control institutional influenza outbreaks and for prophylaxis of influenza exposures that occur before or less than 2 weeks after vaccination with inactivated vaccine, or in years when circulating strains differ from those included in the vaccine. They can also be used for early treatment of patients with influenza.
Update: Influenza Resistance to Amantadine and Rimantadine
The Medical Letter on Drugs and Therapeutics • January 30, 2006; (Issue 1227)
Our article on Antiviral Drugs for Prophylaxis and Treatment of Influenza (Med Lett Drugs Ther 2005;47:93) mentioned possible use of amantadine (Symmetrel, and others) and rimantadine (Flumadine, and others),...
Our article on Antiviral Drugs for Prophylaxis and Treatment of Influenza (Med Lett Drugs Ther 2005;47:93) mentioned possible use of amantadine (Symmetrel, and others) and rimantadine (Flumadine, and others), but warned that the incidence of resistance has increased substantially. The CDC recently issued a Health Alert (www.cdc.gov) saying that current evidence indicates that a high proportion of circulating influenza A viruses in the US are now resistant to amantadine and rimantadine and they should not be used for this indication, at least this year. Click here to go to this update article.
Drugs in the Elderly
The Medical Letter on Drugs and Therapeutics • January 16, 2006; (Issue 1226)
The physiologic changes that occur with aging can affect the pharmacokinetics and pharmacodynamics of many prescription and over-the-counter drugs, increasing the likelihood of adverse...
The physiologic changes that occur with aging can affect the pharmacokinetics and pharmacodynamics of many prescription and over-the-counter drugs, increasing the likelihood of adverse effects.
Antiviral Drugs for Prophylaxis and Treatment of Influenza
The Medical Letter on Drugs and Therapeutics • November 21, 2005; (Issue 1222)
Antiviral prophylaxis is indicated for influenza exposures that occur before (or less than 2 weeks after) vaccination with inactivated vaccine, or in years when circulating strains differ from those included in...
Antiviral prophylaxis is indicated for influenza exposures that occur before (or less than 2 weeks after) vaccination with inactivated vaccine, or in years when circulating strains differ from those included in the vaccine. Antiviral drugs can also be used for treatment of patients who develop symptoms of influenza, regardless of vaccination status.
Please see Update: Influenza Resistance to Amantadine and Rimantadine
Please see Update: Influenza Resistance to Amantadine and Rimantadine
Drugs for Non-HIV Viral Infections
The Medical Letter on Drugs and Therapeutics • April 1, 2005; (Issue 32)
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the tables that begin on page 24. Some of the indications and dosages recommended here have not been approved by the...
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the tables that begin on page 24. Some of the indications and dosages recommended here have not been approved by the FDA.
L-Carnitine
The Medical Letter on Drugs and Therapeutics • November 22, 2004; (Issue 1196)
Carnitine is a naturally occurring amino acid derivative essential for transport of long-chain fatty acids into mitochondria. It is advertised on the Internet as a dietary supplement that can promote weight...
Carnitine is a naturally occurring amino acid derivative essential for transport of long-chain fatty acids into mitochondria. It is advertised on the Internet as a dietary supplement that can promote weight loss, increase energy, enhance athletic performance and slow aging. Levocarnitine (Carnitor - Sigma-Tau) has been FDA approved for oral and parenteral treatment of primary carnitine deficiency since 1986. Products containing levocarnitine and its synthetic derivative acetyl-L-carnitine are available as dietary supplements in the US.
Antiviral Drugs for Prophylaxis and Treatment of Influenza
The Medical Letter on Drugs and Therapeutics • October 25, 2004; (Issue 1194)
Due to the unanticipated shortage in the US supply of inactivated influenza vaccine, many persons who normally would have received the vaccine will be unable to get it this year. Antiviral drugs can be used...
Due to the unanticipated shortage in the US supply of inactivated influenza vaccine, many persons who normally would have received the vaccine will be unable to get it this year. Antiviral drugs can be used for prophylaxis of unvaccinated persons who are exposed to influenza, and for treatment of both vaccinated and unvaccinated patients who develop symptoms of the disease.
Drugs for Parkinson's Disease
The Medical Letter on Drugs and Therapeutics • June 1, 2004; (Issue 22)
Parkinson's disease is caused by progressive degeneration of dopamine-containing neurons in the substantia nigra. Dopamine itself cannot be used to treat Parkinson's disease because it does not cross the...
Parkinson's disease is caused by progressive degeneration of dopamine-containing neurons in the substantia nigra. Dopamine itself cannot be used to treat Parkinson's disease because it does not cross the blood-brain barrier.
Influenza Prevention 2003-2004
The Medical Letter on Drugs and Therapeutics • September 29, 2003; (Issue 1166)
Unlike the last few years there is no early-season shortage of influenza vaccine. Immunization programs for all recommended individuals can proceed. There are 2 new influenza vaccine formulations available...
Unlike the last few years there is no early-season shortage of influenza vaccine. Immunization programs for all recommended individuals can proceed. There are 2 new influenza vaccine formulations available this year, FluMist, an intranasal vaccine and Fluzone, a pediatric formulation. Timing, indications, adverse effects, dosage and cost of the vaccines is discussed. The drugs that can be used for prophylaxis of influenza are also reviewed.
Drugs for Pneumonia
The Medical Letter on Drugs and Therapeutics • September 1, 2003; (Issue 13)
The choice of drugs for treatment of pneumonia depends on the most likely pathogens causing the infection and local antimicrobial resistance patterns. Factors such as severity of illness, presence of co-morbid...
The choice of drugs for treatment of pneumonia depends on the most likely pathogens causing the infection and local antimicrobial resistance patterns. Factors such as severity of illness, presence of co-morbid conditions and whether the infection is community or hospital-acquired also need to be considered.
FluMist: An Intranasal Live Influenza Vaccine
The Medical Letter on Drugs and Therapeutics • August 19, 2003; (Issue 1163)
FluMist (MedImmune), the first live-attenuated and first intranasally administered influenza vaccine, has been approved by the FDA to prevent influenza in healthy people 5-49 years old. Given as a nasal spray,...
FluMist (MedImmune), the first live-attenuated and first intranasally administered influenza vaccine, has been approved by the FDA to prevent influenza in healthy people 5-49 years old. Given as a nasal spray, it stimulates immunity by viral replication in the upper respiratory tract. This vaccine apparently will be advertised directly to the public as a "needle-free" alternative to intramuscular influenza vaccine.
Drugs Past Their Expiration Date
The Medical Letter on Drugs and Therapeutics • October 28, 2002; (Issue 1142)
Physicians and pharmacists are often asked if patients can use drugs after their expiration date. Pharmaceutical companies, because of legal restrictions and liability concerns, will not sanction such use and...
Physicians and pharmacists are often asked if patients can use drugs after their expiration date. Pharmaceutical companies, because of legal restrictions and liability concerns, will not sanction such use and may not even comment on the safety or effectiveness of using their products beyond the date on the label.
Influenza Prevention 2002-2003
The Medical Letter on Drugs and Therapeutics • September 2, 2002; (Issue 1138)
Influenza vaccine for the 2002-2003 season will include last year's A strains, A/New Caledonia/20/99 (H1N1)-like and A/Moscow/10/99 (H3N2)-like, and a new B strain, B/Hong-Kong/330/01-like (MMWR Morb Mortal...
Influenza vaccine for the 2002-2003 season will include last year's A strains, A/New Caledonia/20/99 (H1N1)-like and A/Moscow/10/99 (H3N2)-like, and a new B strain, B/Hong-Kong/330/01-like (MMWR Morb Mortal Wkly Rep 2002; 51:503).
Drugs That May Cause Psychiatric Symptoms
The Medical Letter on Drugs and Therapeutics • July 8, 2002; (Issue 1134)
Many drugs can cause psychiatric symptoms, but a causal connection is often difficult to establish. Psychiatric symptoms that emerge during drug treatment may also be due to the underlying illness, previously...
Many drugs can cause psychiatric symptoms, but a causal connection is often difficult to establish. Psychiatric symptoms that emerge during drug treatment may also be due to the underlying illness, previously unrecognized psychopathology, or psychosocial factors. The withdrawal of some drugs can cause symptoms such as anxiety, psychosis, delirium, agitation or depression.
Drugs for Non-HIV Viral Infections
The Medical Letter on Drugs and Therapeutics • February 4, 2002; (Issue 1123)
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the table that begins on the next page. Since the last Medical Letter issue on this subject, some new drugs and some...
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the table that begins on the next page. Since the last Medical Letter issue on this subject, some new drugs and some new recommendations for old drugs have been added.
Influenza Prevention 2001-2002
The Medical Letter on Drugs and Therapeutics • September 17, 2001; (Issue 1113)
The centers for Disease Control and Prevention is anticipating a delay, but not a shortage, of influenza vaccine for the 2001-2002 season. Last year manufacturing problems led to a substantial delay in vaccine...
The centers for Disease Control and Prevention is anticipating a delay, but not a shortage, of influenza vaccine for the 2001-2002 season. Last year manufacturing problems led to a substantial delay in vaccine availability. This year's delay is being attributed, in part, to the dicontinuation of the Fluogen (King) brand of vaccine. The 2001-02 vaccine will include A/New Caledonia/20/99 (H1N1)-like, A/Moscow/10/99 (H3N2)-like, and B/Sichuan/379/99-like antigens.
Drugs for Non-HIV Viral Infections
The Medical Letter on Drugs and Therapeutics • December 3, 1999; (Issue 1067)
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the [article's]...
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the [article's] table.
Two Neuraminidase Inhibitors for Treatment of Influenza
The Medical Letter on Drugs and Therapeutics • October 8, 1999; (Issue 1063)
Zanamivir, a neuraminidase inhibitor taken by inhalation, has been approved by the FDA for treatment of influenza. Oseltamivir phosphate, an oral neuraminidase inhibitor, will probably be approved...
Zanamivir, a neuraminidase inhibitor taken by inhalation, has been approved by the FDA for treatment of influenza. Oseltamivir phosphate, an oral neuraminidase inhibitor, will probably be approved soon.
Bupropion (Zyban) for Smoking Cessation
The Medical Letter on Drugs and Therapeutics • August 15, 1997; (Issue 1007)
Bupropion hydrochloride, currently available as an antidepressant (Wellbutrin - Medical Letter, 31:97, 1989; Wellbutrin SR), is now being marketed in a sustainedrelease formulation as Zyban (Glaxo Wellcome)...
Bupropion hydrochloride, currently available as an antidepressant (Wellbutrin - Medical Letter, 31:97, 1989; Wellbutrin SR), is now being marketed in a sustainedrelease formulation as Zyban (Glaxo Wellcome) for use as an aid in smoking cessation.
Drugs for Non-HIV Viral Infections
The Medical Letter on Drugs and Therapeutics • August 1, 1997; (Issue 1006)
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the table on the next page. The treatment of HIV infection will be discussed in a future...
The drugs of choice for non-HIV viral infections with their dosages and cost are listed in the table on the next page. The treatment of HIV infection will be discussed in a future issue.
Rimantadine for Prevention and Treatment of Influenza
The Medical Letter on Drugs and Therapeutics • November 26, 1993; (Issue 910)
Rimantadine hydrochloride (Flumadine - Forest), the alpha-methyl derivative of amantadine (Symmetrel, and others), was recently approved by the US Food and Drug Administration for prevention and treatment of...
Rimantadine hydrochloride (Flumadine - Forest), the alpha-methyl derivative of amantadine (Symmetrel, and others), was recently approved by the US Food and Drug Administration for prevention and treatment of influenza A virus infections in adults and for prevention of influenza in children.
Alpha-Galactosidase to Prevent Gas
The Medical Letter on Drugs and Therapeutics • April 2, 1993; (Issue 893)
The enzyme alpha-galactosidase (Beano - AkPharma), derived from a mold and classified as a food, is sold without presecription in pharmacies and food stores. The manufacturer recommends taking the anzyme to...
The enzyme alpha-galactosidase (Beano - AkPharma), derived from a mold and classified as a food, is sold without presecription in pharmacies and food stores. The manufacturer recommends taking the anzyme to decrease intestinal gas producted by eating the high-fiber diets now widely recommended in the USA.
Drugs for Viral Infections
The Medical Letter on Drugs and Therapeutics • April 3, 1992; (Issue 867)
Since the last review of this topic (Medical Letter, 32:73, August 10, 1990) some new antiviral agents have been approved and the indications for several others expanded. The drugs of choice for viral...
Since the last review of this topic (Medical Letter, 32:73, August 10, 1990) some new antiviral agents have been approved and the indications for several others expanded. The drugs of choice for viral infections are listed in the table on page 36.
Drugs for Viral Infections
The Medical Letter on Drugs and Therapeutics • August 10, 1990; (Issue 824)
...
Influenza Prevention, 1989-1990
The Medical Letter on Drugs and Therapeutics • October 20, 1989; (Issue 803)
A new trivalent inactivated influenza vaccine is now available for the 1989-1990 influenza season (Morbid Mortal Weekly Rep, 38:297, May 5, 1989: Can Med Assoc J, 141:425, Spet 1, 1989). Antigens in this...
A new trivalent inactivated influenza vaccine is now available for the 1989-1990 influenza season (Morbid Mortal Weekly Rep, 38:297, May 5, 1989: Can Med Assoc J, 141:425, Spet 1, 1989). Antigens in this years's Vaccine are A/Taiwan/1/86 (H1N1), A/Shanghai/11/87 (H3N2), and B/Yamagata/16/88. The A/Shanghai and B/Yamagata are new strains this year. The vaccine is available in the USA as a split-virus (subvirion) or whole virus preparation from Squibb (Fluzone), as a split-virus preparation from parke-davis (Fluogen) and Wyeth-Ayerst (Influenza Virus Vaccine, Trivalent), and as a purified-surface-antigen formulations may be less likely to cause adverse reactions, especially in children; whole-virus vaccines may be slighltly more antigenic. Vaccine from previous years should not be used.
Influenza Prevention, 1988-1989
The Medical Letter on Drugs and Therapeutics • August 26, 1988; (Issue 773)
A new trivalent inactivated influenza vaccine is now available for the 1988-1989 influenza season (Morbid Mortal Weekly Rep, 37:357, June 17, 1988). Antigens in this year's vaccine are A/Taiwan/1/86 (H1N1),...
A new trivalent inactivated influenza vaccine is now available for the 1988-1989 influenza season (Morbid Mortal Weekly Rep, 37:357, June 17, 1988). Antigens in this year's vaccine are A/Taiwan/1/86 (H1N1), A/Sichuan/2/87 (H3N2), and B/Victoria/2/87. The A/Sichuan is a new strain that caused last year's large outbreak of the disease. The vaccine is available in the USA as a split-virus (Subvirion) or whole virus preparation from Squibb (Fluzone), and as a split-virus preparation from Parke-Davis (Fluogen) and Wyeth (Influenza Virus Vaccine, Trivalent). Split-virus vaccines may be slightly more antigenic. Vaccine from previous years should not be used.